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Ann Rheum Dis:一项研究揭示了髋关节疼痛患者早期髋骨关节炎的10年自然病程

2021-01-20 xiangting MedSci原创

10年随访期间,每9名早期髋关节疼痛的患者中就有1名接受髋关节置换术。

髋关节疼痛在临床上很常见,很多老年人或中年人会出现髋关节疼痛,常见的疾病可能是滑膜炎或骨关节炎等。这项研究目的是探讨初次出现髋关节疼痛的人群中髋骨关节炎(OA)的自然病程。

研究对象为髋关节和膝关节队列研究中的早期症状性髋关节OA患者,收集基线第2、5、8和10年后数据。使用描述性统计方法分析髋关节疼痛的自然病程,其中包括临床体征和症状、躯体功能和影像学骨关节炎(ROA)特征。

结果如下:纳入了588名髋关节疼痛的参与者,其中86%完成了10年随访。10年随访表明,12%的参与者(69名参与者)接受了髋关节置换(HR),髋关节ROA(Kellgren和Lawrence评分≥2)的患病率从19%增至49%根据美国风湿病学会标准,临床髋关节OA的患病率从27%增至43%。10年随访期间,对于没有接受HR的患者,所有的西安大略和麦克马斯特大学骨关节炎指数量表体力活动保持不变。使用止痛药的比例从基线的43%增加到10年后的50%。

10年随访期间,每9名早期髋关节疼痛的患者中就有1名接受了髋关节置换术并且临床髋关节OA和髋关节ROA的患病率稳步上升。该研究发现10年后,初次出现髋关节疼痛要么接受了髋关节置换术,要么症状保持不变

原始出处:

Annemaria C. van Berkel. 10-Year natural course of early hip osteoarthritis in middle-aged persons with hip pain: a CHECK study. Ann Rheum Dis. January 2021.

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    2021-10-29 lisa438
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    2021-07-04 zhaojie88
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1740374, encodeId=2cf01e4037440, content=<a href='/topic/show?id=6f088626603' target=_blank style='color:#2F92EE;'>#自然病程#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86266, encryptionId=6f088626603, topicName=自然病程)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e00d34741921, createdName=siiner, createdTime=Sat Mar 06 09:30:53 CST 2021, time=2021-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2026688, encodeId=3e3f20266881f, content=<a href='/topic/show?id=e0b110159578' target=_blank style='color:#2F92EE;'>#骨关节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101595, encryptionId=e0b110159578, topicName=骨关节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373b263, createdName=lisa438, createdTime=Fri Oct 29 20:30:53 CST 2021, time=2021-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013567, encodeId=5a82201356e47, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jul 04 09:30:53 CST 2021, time=2021-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986828, encodeId=cbeb1986828f6, content=<a href='/topic/show?id=6b393012106' target=_blank style='color:#2F92EE;'>#关节疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30121, encryptionId=6b393012106, topicName=关节疼痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Jul 14 01:30:53 CST 2021, time=2021-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1737150, encodeId=fa851e3715045, content=<a href='/topic/show?id=d8b510206147' target=_blank style='color:#2F92EE;'>#髋关节疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102061, encryptionId=d8b510206147, topicName=髋关节疼痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bd7b34248465, createdName=ms6829001416292975, createdTime=Thu Mar 18 16:30:53 CST 2021, time=2021-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1266257, encodeId=a205126625e93, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Fri Jan 22 03:30:53 CST 2021, time=2021-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918722, encodeId=ba7b918e22ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb355252510, createdName=147e4706m08暂无昵称, createdTime=Thu Jan 21 16:42:37 CST 2021, time=2021-01-21, status=1, ipAttribution=)]
    2021-01-22 lmm397
  7. [GetPortalCommentsPageByObjectIdResponse(id=1740374, encodeId=2cf01e4037440, content=<a href='/topic/show?id=6f088626603' target=_blank style='color:#2F92EE;'>#自然病程#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86266, encryptionId=6f088626603, topicName=自然病程)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e00d34741921, createdName=siiner, createdTime=Sat Mar 06 09:30:53 CST 2021, time=2021-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2026688, encodeId=3e3f20266881f, content=<a href='/topic/show?id=e0b110159578' target=_blank style='color:#2F92EE;'>#骨关节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101595, encryptionId=e0b110159578, topicName=骨关节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373b263, createdName=lisa438, createdTime=Fri Oct 29 20:30:53 CST 2021, time=2021-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013567, encodeId=5a82201356e47, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jul 04 09:30:53 CST 2021, time=2021-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986828, encodeId=cbeb1986828f6, content=<a href='/topic/show?id=6b393012106' target=_blank style='color:#2F92EE;'>#关节疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30121, encryptionId=6b393012106, topicName=关节疼痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Jul 14 01:30:53 CST 2021, time=2021-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1737150, encodeId=fa851e3715045, content=<a href='/topic/show?id=d8b510206147' target=_blank style='color:#2F92EE;'>#髋关节疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102061, encryptionId=d8b510206147, topicName=髋关节疼痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bd7b34248465, createdName=ms6829001416292975, createdTime=Thu Mar 18 16:30:53 CST 2021, time=2021-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1266257, encodeId=a205126625e93, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Fri Jan 22 03:30:53 CST 2021, time=2021-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918722, encodeId=ba7b918e22ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb355252510, createdName=147e4706m08暂无昵称, createdTime=Thu Jan 21 16:42:37 CST 2021, time=2021-01-21, status=1, ipAttribution=)]
    2021-01-21 147e4706m08暂无昵称

    学习了

    0

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