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JACC:二尖瓣反流患者中的左室纤维化情况

2018-08-15 MedSci MedSci原创

近期有研究报道原发性二尖瓣反流(MR)患者的左室纤维化主要是由二尖瓣脱垂(MVP)导致。本研究的目的旨在通过心血管磁共振(CMR)评估MR伴有MVP或者不伴有MVP患者的左室纤维化的发生率、临床特征和预后。本研究对一个大型MR队列中的患者分成了MVP组和非MVP组,主要终点事件是心律失常事件(心源性死亡、心脏骤停和持续性或诱导性室性心律失常)。最终,本研究共纳入356名原发性MR患者,其中177名

近期有研究报道原发性二尖瓣反流(MR)患者的左室纤维化主要是由二尖瓣脱垂(MVP)导致。本研究的目的旨在通过血管磁共振(CMR)评估MR伴有MVP或者不伴有MVP患者的左室纤维化的发生率、临床特征和预后。

本研究对一个大型MR队列中的患者分成了MVP组和非MVP组,主要终点事件是心律失常事件(心源性死亡、心脏骤停和持续性或诱导性室性心律失常)。最终,本研究共纳入356名原发性MR患者,其中177名为MVP组,179名为非MVP组。与非MVP组患者相比,左室纤维化在MVP组更高(36.7% vs. 6.7%; p < 0.001),即使在经临床变量、心脏重塑评估和MR严重程度调整后分析,MVP也是与左室纤维化最相关的因子(OR:6.82; p < 0.001),经过平均1354天时间的随访,MVP组中患有左室纤维化的患者发生心律失常事件的风险最高。

本研究结果显示,在原发性二尖瓣反流患者中,左室纤维化的发生风险在有二尖瓣脱垂的患者中最高,且左室纤维化可作为心律失常事件发生的风险因子。

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    2018-12-23 hbwxf
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    2018-08-17 wwzzly
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    2018-08-16 wxl882001

    了解一下

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1854128, encodeId=0dbd185412820, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sun Dec 23 03:54:00 CST 2018, time=2018-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325934, encodeId=6879132593428, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Aug 17 03:54:00 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463205, encodeId=9274146320593, content=<a href='/topic/show?id=cff92389310' target=_blank style='color:#2F92EE;'>#二尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23893, encryptionId=cff92389310, topicName=二尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fdb26536308, createdName=wwzzly, createdTime=Fri Aug 17 03:54:00 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571622, encodeId=f8df15e1622bb, content=<a href='/topic/show?id=41e33e76137' target=_blank style='color:#2F92EE;'>#反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37761, encryptionId=41e33e76137, topicName=反流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Fri Aug 17 03:54:00 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338996, encodeId=006d3389960d, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu Aug 16 17:13:51 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338978, encodeId=b37a3389e8cd, content=学习了,长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Aug 16 12:49:15 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338775, encodeId=bdf7338e754f, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Wed Aug 15 13:44:59 CST 2018, time=2018-08-15, status=1, ipAttribution=)]
    2018-08-16 1ddf0692m34(暂无匿称)

    学习了,长知识

    0

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    2018-08-15 清风拂面

    谢谢分享学习

    0

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