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J Hypertens:儿童期到成年早期的体重变化与成人高血压风险的关系

2018-12-18 xing.T MedSci原创

由此可见,成年早期超重/肥胖与成人高血压相关,无论儿童期体重如何。相反,如果超重/肥胖儿童成年后体重正常,成人高血压的风险可以逆转。

儿童期超重/肥胖被认为会增加晚年患高血压的风险。然而,很少有研究评估从儿童期到成年期的体重变化轨迹对成人高血压的影响。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,该研究旨在评估中国人群从儿童到成年早期的体重变化与成人高血压之间的关系。

该数据来自于中国健康与营养调查队列研究,其中包括2095名参与者,1991年至2011年期间,他们在儿童期(6-17岁)和成年早期(18-37岁)之间至少测量过一次BMI和血压(BP)。泊松回归模型用于评估从儿童期到成年早期体重变化对成人高血压风险的影响。

中位随访11.0年后,儿童中有235名参与者(11.2%)患有高血压,114名成年参与者(5.4%)患有高血压。与儿童期和成年早期正常体重的受试者(n=1604)相比,成人高血压的相对风险(RR)在儿童期和成年期早期超重/肥胖的个体中为3.79 [95%置信区间(CI)=1.94-7.41](n=79),而对于儿童期正常体重但成年早期超重/肥胖的个体为3.75(95%CI=2.49-5.64)(n=301)。相比之下,儿童期超重/肥胖但成年人体重正常(n=111)的参与者成人高血压风险没有增加(RR=1.05,95%CI=0.33-3.40)。

由此可见,成年早期超重/肥胖与成人高血压相关,无论儿童期体重如何。相反,如果超重/肥胖儿童成年后体重正常,成人高血压的风险可以逆转。

原始出处:

Hou, Yaping.et al.Weight status change from childhood to early adulthood and the risk of adult hypertension. Journal of Hypertension. 2018. https://journals.lww.com/jhypertension/Abstract/publishahead/Weight_status_change_from_childhood_to_early.97300.aspx

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