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Liver Int:锻炼预防超重、肥胖患者发生肝硬化

2017-08-30 MedSci MedSci原创

适度的锻炼可以防止肥胖和超重成年人发生肝硬化。运动时间超过推荐的150分钟/周,获益更多。

超重的肝病患者中锻炼改善了肝酶、胰岛素水平和生活质量。然而,锻炼预防肝硬化的证据还不确凿。因此,开展了一项有关运动对肥胖和超重成年人肝硬化影响的研究。

研究者使用2012年成人预防医疗服务数据集进行评估,并使用国家健康保险研究数据库确定肝硬化。所有参与者年龄≥40岁。采用logistic回归估计肝硬化的优势比。

研究结果表明1586例超重和1525例肥胖成人被确诊为肝硬化。每周锻炼时间超过150分钟对肥胖男性和女性的肝硬化有明显的保护作用。然而,每周锻炼时间少于150分钟仅仅对肥胖男性有保护作用。每周锻炼时间超过150分钟,肥胖男性、肥胖女性肝硬化的优势比分别为0.71(95%可信区间:0.584-0.841)、0.736(95%可信区间:0.562-0.964)。超重男性和女性调整后的优势比分别为0.734(95%可信区间:0.622 - 0.866)和0.503(95%可信区间:0.37-0.684)。每周锻炼时间少于150分钟,超重、肥胖男性优势比分别为0.879 (95%可信区间:0.788-0.980)、0.874 (95%可信区间:0.782-0.977);超重、肥胖女性优势比分别为0.918 (95%可信区间:0.778-1.083)、0.916 (95%可信区间:0.780-1.075)。

适度的锻炼可以防止肥胖和超重成年人发生肝硬化。运动时间超过推荐的150分钟/周,获益更多。

原始出处:

Jan CF, Nfor ON, Huang JY, et al. Exercise Might Prevent Liver Cirrhosis in Overweight and Obese Adults. Liver Int, 2017, Aug 19. doi: 10.1111/liv.13553.

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
    2017-09-15 虈亣靌

    未来的发展前景广阔

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
    2017-09-02 虈亣靌

    好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛.

    0

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    2017-09-02 flysky120

    肥胖带来的疾病太多了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
    2017-09-01 yfjms

    学习了

    0

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