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ANN SURG:胃癌Lauren分型是与术后复发有关的重要因素

2017-12-23 MedSci MedSci原创

很少有研究关注西方患者接受根治性胃癌切除术后复发情况。ANN SURG近期发表了一篇文章,研究胃癌患胃食管交界处癌切除后的复发部位。

很少有研究关注西方患者接受根治性胃癌切除术后复发情况。ANN SURG近期发表了一篇文章,研究胃癌患胃食管交界处癌切除后的复发部位。

作者检索了单中心的数据库,收集了患者临床病理特征,复发部位,无病生存和总生存数据。从2000年1月到2010年6月,共有957例患者接受了胃癌根治性切除术,435例患者出现复发,其中有386例患者的复发部位的完整数据可以获得。206例患者为Lauren肠型,180例患者为弥漫型或混合型。中位复发时间为12个月,75%的复发在2年内出现。肠型和弥漫/混合型之间复发模式存在显着区别。对肠型肿瘤,远处转移(54%)是最常见的部位,而后是局部(20%),腹膜(15%)和多病灶复发(11%)。对弥漫/混合型肿瘤,腹膜复发(37%)最常见,而后是远处转移(32%),局部(22%)和多病灶复发(9%)。多因素分析表明,Lauren病理分型是与腹膜复发和远处复发有关的唯一显着因素。复发后,中位总生存时间只有8.4个月。

文章最后认为,对于切除后出现复发的胃癌患者, 不同Lauren病理类型之间复发模式区别很大。

原始出处:

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    2018-01-12 天涯183

    非常好的文章.学习了

    0

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    2018-01-04 cscdliu

    非常好.学习了

    0

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    2017-12-26 Drhzm308

    呵呵呵.学习了

    0

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    2017-12-23 1e0e5697m83(暂无匿称)

    henhao

    0

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    2017-12-23 swfzhanggui

    非常好.谢谢分享

    0

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    2017-12-23 戒馋,懒,贪

    谢谢分享

    0

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    2017-12-23 Y—xianghai

    学习了新知识

    0

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