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Radiology:胰腺导管内乳头状粘液性肿瘤恶性潜能

2019-12-18 shaosai MedSci原创

背景:胰腺导管内乳头状粘液性肿瘤(IPMNs)临床管理国际指南2017版中更新了一些内容。然而,其诊断价值尚未明确。本研究旨在评估修订版指南预测胰腺IPMN恶性潜能的价值,比较对比增强CT和MRI的诊断价值和设备间一致性。

背景:胰腺导管内乳头状粘液性肿瘤(IPMNs)临床管理国际指南2017版中更新了一些内容。然而,其诊断价值尚未明确。本研究旨在评估修订版指南预测胰腺IPMN恶性潜能的价值,比较对比增强CT和MRI的诊断价值和设备间一致性。

本研究为回顾性研究,由两名放射科医师分析经手术切除证实的胰腺IPMN的增强扫描CT和MRI图像。利用ROC曲线分析CT和MRI的诊断价值。利用加权κ和ICC评价设备间一致性。

结果为,本研究共纳入了86例胰腺IPMN患者。在CT和MRI图像中,恶性IPMN肿增强粘膜结节、主胰管径口节段性变化、淋巴结病变、主胰管管径扩大和囊性病变明显扩大的发生率要明显高于良性IPMN。无论检查类型,增强粘膜结节不小于5mm具有最高的OR值。CT和MRI诊断恶性IPMN的ROC曲线下面积无明显差异,分别为0.83 [95% CI: 0.75, 0.92]) 、 0.86 [95%CI: 0.77, 0.95]),设备间一致性κ = 0.70。

本研究表明,综合修订的CT指标,≥5mm增强粘膜结节与恶性导管内乳头状粘液性肿瘤(IPMN)具有显着相关性,对比增强CT和MRI两种预测恶性IPMN的诊断能力相当。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1992239, encodeId=37561992239da, content=<a href='/topic/show?id=541e46e20fe' target=_blank style='color:#2F92EE;'>#导管内乳头状粘液性肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46720, encryptionId=541e46e20fe, topicName=导管内乳头状粘液性肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Mon Aug 24 04:00:00 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2045026, encodeId=90b42045026fc, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Wed Jul 22 09:00:00 CST 2020, time=2020-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377272, encodeId=b6a23e7272da, content=很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47822969005, createdName=lifeng6035, createdTime=Sun Dec 22 00:37:12 CST 2019, time=2019-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377131, encodeId=83d33e7131d4, content=从影像学角度探讨该类肿瘤的恶性潜能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43a21971117, createdName=njwbhuang, createdTime=Wed Dec 18 20:08:38 CST 2019, time=2019-12-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1992239, encodeId=37561992239da, content=<a href='/topic/show?id=541e46e20fe' target=_blank style='color:#2F92EE;'>#导管内乳头状粘液性肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46720, encryptionId=541e46e20fe, topicName=导管内乳头状粘液性肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Mon Aug 24 04:00:00 CST 2020, time=2020-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2045026, encodeId=90b42045026fc, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Wed Jul 22 09:00:00 CST 2020, time=2020-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377272, encodeId=b6a23e7272da, content=很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47822969005, createdName=lifeng6035, createdTime=Sun Dec 22 00:37:12 CST 2019, time=2019-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377131, encodeId=83d33e7131d4, content=从影像学角度探讨该类肿瘤的恶性潜能。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43a21971117, createdName=njwbhuang, createdTime=Wed Dec 18 20:08:38 CST 2019, time=2019-12-18, status=1, ipAttribution=)]
    2019-12-22 lifeng6035

    很实用

    0

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    2019-12-18 njwbhuang

    从影像学角度探讨该类肿瘤的恶性潜能。

    0

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