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Plos One:耶鲁研究将生育和加速衰老相联系

2016-01-25 佚名 生物谷

在最近发表于Plos One期刊的新研究中,耶鲁大学人类学家揭示了女性生育可能导致加速衰老的首个证据。 研究人员在100位健康绝经后妇女中测试了与加速衰老有关的生物标记物。这些女性来自波兰南部的5个村庄。 这项研究与雅盖隆大学医学院(Jagiellonian University Medical College)和波兰科学院的科学家们合作进行,研究发现:孕次更高的女性--经历更多怀孕、分娩

在最近发表于Plos One期刊的新研究中,耶鲁大学人类学家揭示了女性生育可能导致加速衰老的首个证据。

研究人员在100位健康绝经后妇女中测试了与加速衰老有关的生物标记物。这些女性来自波兰南部的5个村庄。

这项研究与雅盖隆大学医学院(Jagiellonian University Medical College)和波兰科学院的科学家们合作进行,研究发现:孕次更高的女性--经历更多怀孕、分娩,更多时间哺乳--加速衰老的生物标记物水平高于孕次较低的女性。

经历至少4次怀孕的女性,DNA氧化损伤生物标记物8-OHdG的水平高出20%。身体主要氧化防御酶Cu-Zn SOD水平高出60%,表明氧化应激增加,这是衰老的一个重要促进因素。

这种生育和加速老化之间的生物联系已经在动物被记录,但在人类中从未如此明显。

"和所有生物一样,人们面临繁育和孕妇所在地能量资源有限之间的权衡"该研究共同作者、耶鲁大学人类学教授、生态学和进化生物学教授Richard Bribiescas说,"这项研究首次提供了人类中这种取舍的令人信服的证据。"

原始出处:

Anna Ziomkiewicz,Amelia Sancilio,et al, Evidence for the Cost of Reproduction in Humans: High Lifetime Reproductive Effort Is Associated with Greater Oxidative Stress in Post-Menopausal Women.plos one.2015

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1789774, encodeId=c38c1e897743a, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Feb 17 02:03:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60829, encodeId=913860829ca, content=向母亲致敬, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 13:00:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60828, encodeId=ed5a60828e8, content=有关系的, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 12:59:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59375, encodeId=4929593e57f, content=母亲把自己所有的精华都献给给了自己的孩子,能不老吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4371683642, createdName=文医生, createdTime=Tue Jan 26 13:40:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1789774, encodeId=c38c1e897743a, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Feb 17 02:03:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60829, encodeId=913860829ca, content=向母亲致敬, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 13:00:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60828, encodeId=ed5a60828e8, content=有关系的, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 12:59:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59375, encodeId=4929593e57f, content=母亲把自己所有的精华都献给给了自己的孩子,能不老吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4371683642, createdName=文医生, createdTime=Tue Jan 26 13:40:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
    2016-01-27 李继凯

    向母亲致敬

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1789774, encodeId=c38c1e897743a, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Feb 17 02:03:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60829, encodeId=913860829ca, content=向母亲致敬, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 13:00:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60828, encodeId=ed5a60828e8, content=有关系的, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 12:59:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59375, encodeId=4929593e57f, content=母亲把自己所有的精华都献给给了自己的孩子,能不老吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4371683642, createdName=文医生, createdTime=Tue Jan 26 13:40:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
    2016-01-27 李继凯

    有关系的

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1789774, encodeId=c38c1e897743a, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Feb 17 02:03:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60829, encodeId=913860829ca, content=向母亲致敬, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 13:00:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60828, encodeId=ed5a60828e8, content=有关系的, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 12:59:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59375, encodeId=4929593e57f, content=母亲把自己所有的精华都献给给了自己的孩子,能不老吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4371683642, createdName=文医生, createdTime=Tue Jan 26 13:40:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
    2016-01-26 文医生

    母亲把自己所有的精华都献给给了自己的孩子,能不老吗

    0

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