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Circ Cardiovasc Imaging:使用心脏磁共振评估南美锥虫病右心室收缩功能!

2017-03-20 xing.T MedSci原创

在慢性南美锥虫病患者中,右心室收缩功能障碍更常见于左心室收缩功能障碍的患者,虽然孤立性和早期右心室功能不全也有被发现。

右心室功能障碍被认为是南美锥虫病明显的全身性淤血的原因。然而,在南美锥虫病的原发性右心功能障碍的发生仍然存有争议。最近,血管领域权威杂志Circulation-Cardiovascular Imaging上发表了一篇研究文章。研究人员旨在用心脏磁共振查来评估南美锥虫病患者的右心室收缩功能。

在这项横断面研究中,研究人员共纳入了158例慢性南美锥虫病患者,并且这些患者均接受了心脏磁共振检查。右心室收缩功能障碍被定义为右心室射血分数降低,根据预先设定的针对年龄和性别的临界值。研究人员采用多变量Logistic回归分析来验证右心室收缩功能障碍与年龄、性别、功能分级、心力衰竭用药、心房颤动和左心室收缩功能不全之间的相关性。

参与者的平均年龄为54±13岁,男性占51.2%。58例(37%)患者出现了右心室收缩功能障。虽然通常与左心室射血分数降低相关,研究人员发现有7例(4.4%)患者为孤立的右心室收缩功能障碍,其中2例发生在南美锥虫病的早期阶段。在不确定的/消化型南美锥虫病患者中右心室功能障碍(35.7%)与Chagas心肌病(36.8%)比较没有明显差异(P=1.00)。

在慢性南美锥虫病患者中,右心室收缩功能障碍更常见于左心室收缩功能障碍的患者,虽然孤立性和早期右心室功能不全也有被发现。

原始出处:

Henrique T. Moreira,et al. Evaluation of Right Ventricular Systolic Function in Chagas Disease Using Cardiac Magnetic Resonance Imaging. Circ Cardiovasc Imaging. 2017. https://doi.org/10.1161/CIRCIMAGING.116.005571

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    2017-06-20 quxin068
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    2017-03-24 虈亣靌

    学习新知识谢谢分享

    0

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首都医科大学宣武医院神经内科韩璎教授团队利用多模态磁共振成像技术发现,主观认知下降人群在大脑中阿尔茨海默病易受损的默认网络区域有功能活动增强,可能为弥补情景记忆的减退起到功能代偿。该研究为早期识别主观认知下降提供了影像学证据,并揭示了主观认知下降人群总体记忆水平仍能维持在正常范围内的代偿机制。相关研究成果日前发表于国际权威期刊《Radiology》上。主观认知下降,即自我感觉记忆力减退,比如有时想

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