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Neurology:美国神经病学学会共济失调治疗相关证据研究

2018-02-10 zhangfan MedSci原创

美国神经病学学会就共济失调治疗的相关证据进行系统地回顾研究

近日,美国神经病学学会就共济失调治疗的相关证据进行系统地回顾研究。

其研究结论如下:

1、对于2型发作性共济失调患者,每日15mg的4-氨基吡啶治疗3个月可降低共济失调发作频率(证据等级1);

2、对于混合型共济失调患者,利鲁唑治疗8周可改善共济失调症状(证据等级1);

3、对于弗里德里希共济失调或脊髓小脑共济失调(SCA)患者,利鲁唑治疗12个月可改善共济失调症状。(证据等级1)

4、对于3型SCA患者,每天1200mg的丙戊酸治疗可改善症状;对于脊髓小脑变性患者,促甲状腺激素释放激素治疗10-14天可部分改善共济失调症状(证据等级2);

5、对于3型步态SCA患者,48周的锂盐治疗效果不显著(证据等级1);

6、对于弗里德里希共济失调患者,脱发倾向可能导致症状在6个月内恶化(证据等级2);

7、退化性共济失调患者4周的非药物住院康复治疗可能会改善共济失调和功能(证据等级1);

8、经颅磁刺激可改善小脑运动征象(证据等级1);

9、对于多发性硬化相关共济失调患者,与单纯神经肌肉康复相比,压力夹板治疗无额外益处(证据等级2);

10、数据不足以支持或驳斥随机全身振动疗法的使用(证据等级2)。

原始出处:


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    2018-06-07 yinhl1978
  2. [GetPortalCommentsPageByObjectIdResponse(id=2000311, encodeId=a5b72000311ec, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Jun 07 22:03:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491304, encodeId=e6371491304ff, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Mon Feb 12 00:03:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286991, encodeId=f641286991fb, content=美国神经病学学会共济失调治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Feb 11 07:07:07 CST 2018, time=2018-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286760, encodeId=9c9a286e60c9, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Feb 10 09:37:09 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
    2018-02-12 axin012
  3. [GetPortalCommentsPageByObjectIdResponse(id=2000311, encodeId=a5b72000311ec, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Jun 07 22:03:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491304, encodeId=e6371491304ff, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Mon Feb 12 00:03:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286991, encodeId=f641286991fb, content=美国神经病学学会共济失调治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Feb 11 07:07:07 CST 2018, time=2018-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286760, encodeId=9c9a286e60c9, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Feb 10 09:37:09 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
    2018-02-11 jyzxjiangqin

    美国神经病学学会共济失调治疗.

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2000311, encodeId=a5b72000311ec, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Jun 07 22:03:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491304, encodeId=e6371491304ff, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Mon Feb 12 00:03:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286991, encodeId=f641286991fb, content=美国神经病学学会共济失调治疗., beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Feb 11 07:07:07 CST 2018, time=2018-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286760, encodeId=9c9a286e60c9, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Feb 10 09:37:09 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
    2018-02-10 龙胆草

    学习谢谢分享

    0

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