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BMC Cardiovasc Disord:解放军总医院陈韵岱等研究称,睡眠呼吸暂停者支架置入30天内易出现支架血栓

2017-08-25 朱柳媛 中国循环杂志

解放军总医院陈韵岱等发现,阻塞性睡眠呼吸暂停是冠脉介入治疗后早期(30天内)支架血栓形成的独立危险因素。

解放军总医院陈韵岱等发现,阻塞性睡眠呼吸暂停是冠脉介入治疗后早期(30天内)支架血栓形成的独立危险因素。

研究中,在校正年龄、性别、肥胖、吸烟、高血压糖尿病、高脂血症、急诊手术、替罗非班应用、他汀应用、支架长度等因素后,冠脉介入术后患者中,有阻塞性睡眠呼吸暂停的人出现早期支架血栓形成的风险增加6.34倍。

在没有或只有一个传统心血管病危险因素的患者中,有阻塞性睡眠呼吸暂停者早期支架血栓形成风险尤其高,较没有睡眠呼吸暂停的人增加16倍。

研究者开展了一项病例对照研究,以23例经冠脉造影证实冠脉介入术后有早期血栓形成的患者作为病例组,以92例冠脉介入术后2年随访期间没有出现支架血栓形成的患者作为对照组。

研究者指出,在出现早期支架血栓形成的患者中,阻塞性睡眠呼吸暂停的患病率高达61%,而对照组仅23%。

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    2018-02-18 smlt2008
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replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Thu Jun 14 04:32:00 CST 2018, time=2018-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989204, encodeId=6b32198920416, content=<a href='/topic/show?id=b82ae29925c' target=_blank style='color:#2F92EE;'>#睡眠呼吸暂停者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72992, encryptionId=b82ae29925c, topicName=睡眠呼吸暂停者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=310e209, createdName=yzh399, createdTime=Thu Apr 26 09:32:00 CST 2018, time=2018-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923465, encodeId=5ff819234659b, content=<a href='/topic/show?id=ef2f52e50d4' target=_blank style='color:#2F92EE;'>#总医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52750, encryptionId=ef2f52e50d4, topicName=总医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Sep 21 05:32:00 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1764093, encodeId=fb361e6409307, content=<a href='/topic/show?id=d76d9102e83' target=_blank style='color:#2F92EE;'>#解放军总医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91027, encryptionId=d76d9102e83, topicName=解放军总医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sun Jan 28 21:32:00 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938746, encodeId=c0ff1938e46b6, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Feb 15 22:32:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012388, encodeId=1d552012388fc, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jan 24 11:32:00 CST 2018, time=2018-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582571, encodeId=0d0f15825e132, content=<a href='/topic/show?id=c1695e118ac' target=_blank style='color:#2F92EE;'>#支架血栓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57118, encryptionId=c1695e118ac, topicName=支架血栓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b83016955660, createdName=ms1779634646866130, createdTime=Sun Aug 27 05:32:00 CST 2017, time=2017-08-27, status=1, ipAttribution=)]
    2018-06-14 cmsvly
  5. [GetPortalCommentsPageByObjectIdResponse(id=1989057, encodeId=3d99198905ea9, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Oct 25 13:32:00 CST 2017, time=2017-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977780, encodeId=603a19e7780bc, content=<a href='/topic/show?id=93a211600a' target=_blank style='color:#2F92EE;'>#30天#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1160, encryptionId=93a211600a, topicName=30天)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Sun Feb 18 11:32:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974758, encodeId=912119e475863, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Tue Mar 27 16:32:00 CST 2018, time=2018-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1784394, encodeId=eb4f1e8439446, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, 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style='color:#2F92EE;'>#总医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52750, encryptionId=ef2f52e50d4, topicName=总医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Sep 21 05:32:00 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1764093, encodeId=fb361e6409307, content=<a href='/topic/show?id=d76d9102e83' target=_blank style='color:#2F92EE;'>#解放军总医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91027, encryptionId=d76d9102e83, topicName=解放军总医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sun Jan 28 21:32:00 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938746, encodeId=c0ff1938e46b6, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Feb 15 22:32:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012388, encodeId=1d552012388fc, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jan 24 11:32:00 CST 2018, time=2018-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582571, encodeId=0d0f15825e132, content=<a href='/topic/show?id=c1695e118ac' target=_blank style='color:#2F92EE;'>#支架血栓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57118, encryptionId=c1695e118ac, topicName=支架血栓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b83016955660, createdName=ms1779634646866130, createdTime=Sun Aug 27 05:32:00 CST 2017, time=2017-08-27, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1989057, encodeId=3d99198905ea9, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Oct 25 13:32:00 CST 2017, time=2017-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977780, encodeId=603a19e7780bc, content=<a href='/topic/show?id=93a211600a' target=_blank style='color:#2F92EE;'>#30天#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1160, encryptionId=93a211600a, topicName=30天)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, 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style='color:#2F92EE;'>#总医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52750, encryptionId=ef2f52e50d4, topicName=总医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1d2500084, createdName=1249884fm87暂无昵称, createdTime=Thu Sep 21 05:32:00 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1764093, encodeId=fb361e6409307, content=<a href='/topic/show?id=d76d9102e83' target=_blank style='color:#2F92EE;'>#解放军总医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91027, encryptionId=d76d9102e83, topicName=解放军总医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sun Jan 28 21:32:00 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938746, encodeId=c0ff1938e46b6, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Feb 15 22:32:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012388, encodeId=1d552012388fc, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, 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  7. [GetPortalCommentsPageByObjectIdResponse(id=1989057, encodeId=3d99198905ea9, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Oct 25 13:32:00 CST 2017, time=2017-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977780, encodeId=603a19e7780bc, content=<a href='/topic/show?id=93a211600a' target=_blank style='color:#2F92EE;'>#30天#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1160, encryptionId=93a211600a, topicName=30天)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, 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  8. 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    2018-02-15 quxin068
  9. 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术后补充氧气可以改善氧合和减少AHI,并不增加呼吸暂停低通气事件的持续时间或PtcCO2水平。当补充氧气时少数患者出现显著的CO2潴留。

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最近,有研究人员调查了具有中耳声传递的阻塞性睡眠呼吸暂停综合征(OSA)与耳蜗功能的关系。研究人员根据全睡眠多导图描记术规范和无副发病变对患有和不患有轻度、中等程度和重度OSA男性个体进行了研究。研究群体中的BMI不小于40kg/m2、现在或者过去OSA的治疗、患有心力衰竭、糖尿病、高血压、血脂异常、中风、慢性药物的使用和以前听力损伤历史风险的个体被排除。并对所有合格的参与者进行了完整的多导睡眠描

2017 共识指南:阻塞性睡眠呼吸暂停减重手术围术期管理

世界范围内,减重和代谢手术不断增加,平均每年已超过500,000例。在接受减重代谢手术的患者中约有35%-94%的患者存在阻塞性睡眠呼吸暂停,本文主要针对该类患者接受减重手术的围术期管理提供指导意见。由15位国际专家组成专家小组针对术前筛查,治疗,术后监测,麻醉护理以及随访等内容共提出了58条声明和建议。

Neurology:帕金森病与阻塞性睡眠呼吸暂停患者的认知功能降低!

由此可见,OSA与PD患者嗜睡和认知功能障碍有关,提示OSA可能是这些NMS的可逆因素。需要进一步的研究来评估OSA治疗可否改善PD患者的嗜睡和认知功能障碍。

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