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空气净化器还能降压!?Hypertension杂志分析

2020-06-04 朱朱 中国循环杂志

6月1日,Hypertension杂志在线发表的一项系统综述和Meta分析表明,家庭用细微颗粒空气过滤器可能有助于降低血压。

61日,Hypertension杂志在线发表的一项系统综述和Meta分析表明,家庭用细微颗粒空气过滤器可能有助于降低血压。
 
该分析一共纳入10项随机对照研究,均观察不吸烟者(一共604人)在无烟家庭中使用真的或假的空气净化器时血压的变化。
 
结果发现,平均使用空气净化器13.5天后,这些不吸烟的人平均收缩压大约降低了4 mmHg,舒张压略有下降(-0.95 mmHg),但没有达到统计学差异。
 
亚组分析表明,在不同年龄、细颗粒物暴露水平、研究时间、心肺危险因素、用药情况等条件下,空气净化器均有助于降低收缩压。
 
研究者指出,该分析得出的结果是比较显著的,因为从人群层面来看,血压即便小幅降低,也可导致心血管病发生率和死亡率明显下降。
 
据估计,人群平均收缩压降低5 mmHg,因中风死亡、发生冠心病、全因死亡的风险分别会降低14%9%7%
 
在该Meta分析中,应用空气净化器后短期内收缩压即可下降约4 mmHg,长期持续应用可能会带来明显的健康获益。
 
他们表示,空气净化器是一种价格较便宜、且购买方便的设备,可能是一种有效的心脏保护干预手段,医生可考虑推荐大众尤其高危人群使用空气净化器。
 
不过,研究者表示,由于这些研究的设计存在差别,因此该分析结果需要其他研究来证实。另外,使用个别空气净化器带来的降压获益需要更好地进行量化。
 
其中9项研究的研究时间平均为9天,其余1项研究随访时间长达1年。
 
在所有研究中,应用空气净化器后,室内PM2.5浓度降低了56%
 
来源:Effects of Home Particulate Air Filtration on Blood Pressure: A Systematic Review. Hypertension, 1 Jun 2020

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