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Sleep:认知行为疗法可作为预防抑郁症的一种干预措施

2020-06-29 MedSci原创 MedSci原创

失眠是抑郁症的常见前兆;然而,失眠治疗预防抑郁症的潜力尚未得到证实。失眠的认知行为疗法(CBT-I)可以有效地减少失眠和抑郁的并发症状,并且可以以数字方式提供(dCBT-I);然而,治疗失眠是否会导致

失眠是抑郁症的常见前兆;然而,失眠治疗预防抑郁症的潜力尚未得到证实。失眠的认知行为疗法(CBT-I)可以有效地减少失眠和抑郁的并发症状,并且可以以数字方式提供(dCBT-I);然而,治疗失眠是否会导致抑郁症的持续减少和预防仍不清楚。本随机对照试验考察了dCBT-I在1年随访期内减少和预防抑郁症的疗效。

 

将患有DSM-5失眠症的患者随机分配接受dCBT-I或注意力对照。随访样本包括358名dCBT-I条件的患者和300名在线睡眠教育条件的患者。主要结果测量是1年随访时抑郁症的相对率比。失眠对治疗的反应也被测试为1年随访时抑郁事件的预测因素。

 

结果,在1年的随访中,dCBT-I条件下的抑郁症严重程度相对于对照组继续显著降低。此外,在1年随访中,dCBT-I状态下报告没有抑郁症的个体数量相对于对照组高出51%。在那些基线时有轻微或无抑郁症的人中,相对于对照组,dCBT-I状态下1年随访中度至严重抑郁症的发生率降低了一半。

 

综上所述,该研究结果表明,dCBT-I作为一种预防抑郁症的干预措施,显示出强大的效果。今后的研究应研究剂量-反应要求,并进一步确定dCBT-I预防抑郁症的作用机制。

 

原始出处:

 

Philip ChengDavid A Kalmbach, et al., Depression Prevention via Digital Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial. Sleep. 2019 Oct 9;42(10):zsz150. doi: 10.1093/sleep/zsz150.

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    2021-01-22 蕾蕾

    有用,收藏

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