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J Clin Periodontol: 人群中幽门螺杆菌抗体水平与牙周炎关系

2018-09-10 MedSci MedSci原创

之前有中国的小型研究表明,可以通过牙周治疗减少幽门螺杆菌,但是结果不具有普遍性。本实验使用了波美拉尼亚健康研究中基于人群的数据,评估抗幽门螺杆菌IgG滴度水平与牙周病的关系。

之前有中国的小型研究表明,可以通过牙周治疗减少幽门螺杆菌,但是结果不具有普遍性。本实验使用了波美拉尼亚健康研究中基于人群的数据,评估抗幽门螺杆菌IgG滴度水平与牙周病的关系。

牙周袋深度作为主要的暴露,我们将年龄范围限制为小于60岁的参与者(n = 2,481),以避免在该横断面研究中由于无牙症引起的选择偏倚。对于长达81岁的整个年龄段,我们选择缺牙数(n = 3,705)用以研究。

结果:牙周袋深度与结果之间的关联很弱。由于缺失牙齿数量的上限效应(序数逻辑回归;四分位间距效应的优势比= 1.6; 95%CI:1.3-1.9;线性p值= 0.005),我们检查佩戴可摘义齿是否与较高的抗H滴度水平相关(优势比= 1.3; 95%CI:1.1-1.5)。

结论:欧洲国家一般人群中牙齿脱落和佩戴可摘义齿与较高的抗HIgG滴度水平轻中度相关。

原始出处:

Christian Schwahn, et al.Reducing uncertainty in estimating associations of oral exposures with Helicobacter pylori serology in the general population. Journal of Clinical Periodontology. 2018 September. doi:10.1111/jcpe.12983

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    2024-01-07 zs-wwy 来自广东省

    学习了,受益

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    2018-10-25 kcb069
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    2018-12-10 feather89
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