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Diabetes Care:1型糖尿病患者心电图异常与心血管疾病风险有啥关系?

2017-03-17 xing.T MedSci原创

由此可见,主要心电图异常与1型糖尿病患者CVD风险增加相关。这表明在1型糖尿病患者中进行心电图筛查以筛选CVD风险高风险个体的潜在作用。

近日,糖尿病领域权威杂志Diabetes Care上发表了一研究文章,研究人员旨在评估1型糖尿病患者常见心电图(ECG)异常的患病率和发病率与血管疾病(CVD)发生之间的相关性。

这是一项纵向队列研究纳入了1306例来自于糖尿病控制和并发症试验/糖尿病干预和并发症的流行病学(DCCT/EDIC)研究的1型糖尿病的患者(平均年龄为35.5±6.9岁;女性占47.7%)。心电图异常是根据明尼苏达代码ECG分类被定义为主要、轻微或没有异常。血管事件被定义为首次心肌梗死卒中、确诊的心绞痛、冠状动脉血运重建、充血性心力衰竭或任何CVD死亡。

在中位随访了19年期间,155名参与者(11.9%)发生了心血管事件。在调整了人口和潜在混杂因素的多变量Cox比例风险模型中,任何主要心电图异常的存在作为随着时间变化的协变量与CVD事件风险增加超过2倍相关(风险比为2.10[95%可信区间为1.26-3.48] vs. 无异常/正常ECG,以及2.19[1.46-3.29] vs. 无主要异常)。此外,每次随访(年)中,主要心电图异常的诊断与心血管疾病的风险增加30%相关(风险比为1.30[95%可信区间为1.14-1.48])。轻微的心电图异常与显著增加的CVD风险不相关。

由此可见,主要心电图异常与1型糖尿病患者CVD风险增加相关。这表明在1型糖尿病患者中进行心电图筛查以筛选CVD风险高风险个体的潜在作用。

原始出处:

Elsayed Z. Soliman, et al. Electrocardiographic Abnormalities and Cardiovascular Disease Risk in Type 1 Diabetes: The Epidemiology of Diabetes Interventions and Complications (EDIC) Study.Diabetes Care 2017 Mar; dc162050. https://doi.org/10.2337/dc16-2050

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createdName=仁心济世, createdTime=Sun Mar 19 04:35:00 CST 2017, time=2017-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629718, encodeId=503d1629e18cc, content=<a href='/topic/show?id=7d5b51209d6' target=_blank style='color:#2F92EE;'>#心电图异常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51209, encryptionId=7d5b51209d6, topicName=心电图异常)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c1e521353098, createdName=医生2401, createdTime=Sun Mar 19 04:35:00 CST 2017, time=2017-03-19, status=1, ipAttribution=)]
    2017-03-20 卡圣

    感谢分享,长见识了

    0

  6. 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createdName=仁心济世, createdTime=Sun Mar 19 04:35:00 CST 2017, time=2017-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629718, encodeId=503d1629e18cc, content=<a href='/topic/show?id=7d5b51209d6' target=_blank style='color:#2F92EE;'>#心电图异常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51209, encryptionId=7d5b51209d6, topicName=心电图异常)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c1e521353098, createdName=医生2401, createdTime=Sun Mar 19 04:35:00 CST 2017, time=2017-03-19, status=1, ipAttribution=)]
    2017-03-19 绛珠草小姐

    认真学习,谢谢分享

    0

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