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European Radiology:MRI在上外侧腔内妊娠和间质部妊娠鉴别诊断中的价值

2022-09-07 shaosai MedSci原创

磁共振成像(MRI)具有良好的观察者内部和观察者之间的一致性以及极高的软组织对比度,可以对多种植入部位进行识别,并在多切面视图中区分新鲜血液和其他液体聚集。

上外侧腔内妊娠,以前称为角妊娠,是一种潜在的、偏心的、位于正常子宫角部的腔内妊娠。虽然终止上侧腔内妊娠可以避免子宫破裂的风险,但期待性随访仍是一种选择。如果处理得当,上侧腔内妊娠的活产率可高达80%。区分上侧腔内妊娠和其他子宫输卵管交界处的异位妊娠是一个极具挑战性的项目,其中间质部妊娠是最常见的异位妊娠,占异位妊娠的2-4%,但产妇死亡率比其他类型的异位妊娠高7倍。因此在怀孕前三个月对上侧腔内妊娠和间质部妊娠进行精确诊断至关重要

磁共振成像(MRI)具有良好的观察者内部和观察者之间的一致性以及极高的软组织对比度,可以对多种植入部位进行识别,并在多切面视图中区分新鲜血液和其他液体聚集。因此,MRI对上侧腔内妊娠和间质部妊娠的鉴别诊断有独特的优势。

近日,发表在European Radiology杂志的一项研究评估了通过MRI对上外侧宫腔内妊娠和间质部妊娠进行术前精确区分的能力,为临床的早期准确诊断及诊疗方案的制定提供了支持。

项回顾性研究纳入了59术前影像学诊断为子宫管交界处妊娠患者(2016年1月-2021年7月)。以手术和病理报告为参考标准,我们确定了22名上侧腔内(角)妊娠的患者和37名间质部妊娠的患者。两位资深放射科医生在对患者信息保密的情况下,MRI图像进行判析,并根据原始解释标准确定了每个MRI特征。任何不同意见都通过讨论来解决,以达成共识。根据参考标准计算每个MRI特征的敏感性和特异性。 

腔内妊娠组的子宫内膜厚度大于间质组(P = 0.001)。子宫内膜厚度的临界值为11.5毫米,敏感性、特异性和曲线下面积分别为77.3%、64.9%和0.743。诊断上侧腔内妊娠的两个关键特征是 "内侧游离边缘 "和 "内侧游离边缘加上高于截断值的子宫内膜厚度"。内侧游离缘的敏感性和特异性分别为100%和94.9%。内侧游离边缘加截断值以上的子宫内膜厚度的敏感性和特异性分别为77.3%和100%。诊断间质部妊娠的关键特征是 "完整的外侧交界区",其敏感性和特异性分别为94.6%和100%。 


 24岁的上外侧腔内妊娠患者的核磁共振和宫腔镜检查图像。a 矢状面脂肪抑制T2WI显示子宫内膜厚度(双端箭头)为22.0mm;b 冠状面T2WI和(c)轴向脂肪抑制T2WI显示孕囊(星形)和内侧自由边缘(箭头);d 宫腔镜视图显示孕囊的宫内暴露部分形成自由边缘(黄色箭头)

本研究表明,MRI是诊断上外侧腔内和间质部妊娠的一个有价值的影像学手段,特别是间质部妊娠的孕囊突入子宫腔时价值最大。本研究提供的证据将有助于实现对这两种妊娠状态的精确诊断和治疗策略优化。

 

原文出处:

Wenjuan Liu,Weili Xie,Hang Zhao,et al.Using MRI to differentiate upper-lateral intracavitary pregnancy and interstitial pregnancy for the patients with pregnancies in the uterotubal junction during the first trimester.DOI:10.1007/s00330-022-08786-4

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    2022-10-20 feather89
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    2022-09-07 医鸣惊人

    认真学习了

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