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Childs Nerv Syst:弥散核磁共振成像在小儿脑损伤中的应用

2017-11-30 cuiguizhong MedSci原创

美国加利福尼亚州USC凯克医学院影像遗传学中心的Marina del Rey丹尼斯EL近日在Childs Nerv Syst发表了他们的一项工作,系统性的总结了弥散核磁共振成像在小儿脑损伤中的研究现状。

美国加利福尼亚州USC凯克医学院影像遗传学中心的Marina del Rey丹尼斯EL近日在Childs Nerv Syst发表了他们的一项工作,系统性的总结了弥散核磁共振成像在小儿脑损伤中的研究现状。

创伤性脑损伤(TBI)是世界范围内的重大公共卫生问题。因为TBI会破坏认知和社会发展,对儿童造成重大的破坏性影响。创伤性脑损伤后,白质(WM)特别容易受到破坏,因为在此期间髓鞘化正在进行。扩散核磁共振成像(dMRI)是识别和量化WM破坏的一种多功能方式,可以检测弥漫性轴索损伤(DAI或TAI(创伤性轴索损伤))。

本综述涵盖儿科创伤性脑损伤的扩散核磁共振成像(dMRI)研究,从轻度至重度损伤,涵盖损伤后的所有时期。虽然我们通过使用dMRI了解小儿TBI有了相当大的进展,但是我们的知识仍然存在很大的差距,这可以通过更大规模的研究和更多的纵向研究来弥补。在所有TBI研究中,异质性损伤是一个难点。但研究者预计,更大更好特征化的样本将有助于确定儿科TBI患者群体中的亚组,这对于临床治疗具有重要的意义。

原文出处:

Dennis, E.L., et al., Diffusion MRI in pediatric brain injury. Childs Nerv Syst, 2017. 33(10): p. 1683-1692.

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    2017-12-01 1ddf0692m34(暂无匿称)

    学习了.好文章

    0

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    2017-12-01 执着追梦

    学习.谢谢分享

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