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Sci Rep:部分和根治性肾切除术中,术中尿量和术后急性肾损伤相关性不同

2019-02-08 AlexYang MedSci原创

最近,有研究人员调查了术中尿量和术后急性肾损伤(AKI)相关性在在经历根治性和部分肾切除患者中的情况。研究人员回顾性的分析了742名患者的数据,术后AKI通过肾脏疾病来定义。根治性和部分肾切除术中的术中尿量和AKI风险之间的关系通过多变量逻辑回归分析来进行评估。研究人员还利用最小P值方法来调查与AKI风险相关的术中少尿最优阈值。研究发现,部分肾切除术后,AKI的发生率为14.4%(67/466);

最近,有研究人员调查了术中尿量和术后急性肾损伤(AKI)相关性在在经历根治性和部分肾切除患者中的情况。

研究人员回顾性的分析了742名患者的数据,术后AKI通过肾脏疾病来定义。根治性和部分肾切除术中的术中尿量和AKI风险之间的关系通过多变量逻辑回归分析来进行评估。研究人员还利用最小P值方法来调查与AKI风险相关的术中少尿最优阈值。研究发现,部分肾切除术后,AKI的发生率为14.4%(67/466);根治性肾切除术后,AKI的发生率为57.6%(159/276)。对部分肾切除术,多变量分析表明了肾缺血时间、手术时间、开放手术和术中输液均与AKI显著相关。对根治性肾切除术,高血压历史、基线肾小球滤过率和术中平均排尿量均与AKI显著相关。另外,根治性切除术后,根治性肾切除手术中的术中平均排尿量与AKI相关,而在部分肾切除术后并没有上述相关性。

最后,研究人员指出,平均尿液排量小于1ml/kg/h为根治性肾切术的最优截断值。术中少尿可能在部分和根治性肾切除中具有不同的应用。

原始出处:


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    2019-02-10 jeanqiuqiu
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    2019-02-09 医者仁心5538

    学习了

    0

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