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Int J Pediatr Otorhinolaryngol:不同年龄段的先天性耳聋儿童对圆窗膜电刺激的电诱发听觉脑干反应

2021-07-09 AlexYang MedSci原创

电诱发听觉脑干反应(eABR)是一种客观和有效的方法,用以评估听觉传导途径的功能,直至脑干水平。eABR可以在电刺激听觉神经末梢的螺旋神经节细胞后的前10毫秒内从头皮上记录,它触发了听觉神经和脑干产生

电诱发听觉脑干反应(eABR)是一种客观和有效的方法,用以评估听觉传导途径的功能,直至脑干水平。eABR可以在电刺激听觉神经末梢的螺旋神经节细胞后的前10毫秒内从头皮上记录,它触发了听觉神经和脑干产生一系列的电活动,并可用来估计螺旋神经节细胞的存活率,并能够反映周围听觉通路中神经编码的关键同步成分。eABR组分的起源与由听觉刺激诱发的听觉脑干反应(ABR)组分基本相似,第三波(eIII)认为产生于中脑干,第五波(eV)产生于上脑干。

近期,有研究人员调查了电诱发听觉脑干反应(eABRs)对圆窗龛(RWN)和圆窗膜(RWM)电刺激的作用,以及耳聋持续时间对听觉通路到脑干水平功能的影响

研究人员根据人工耳蜗(CI)植入时的年龄,将99名重度感音神经性听力损失儿童分为四组:≤12个月(A组),13-36个月(B组),37-60个月(C组)和>60个月(D组)。在CI使用期间,通过电刺激RWN和RWM来诱发eABRs。

研究结果发现,RWM刺激的eABR提取率比RWN刺激更高,且阈值更低。四组中RWM刺激的eⅢ延迟和eⅢ-eⅤ延迟间隔相似。然而,早期CI(A组)儿童的eⅤ潜伏期明显短于其他儿童。

RWN和RWM中电刺激诱导的eABR比较

综上所述,与RWN相比,RWM的电刺激诱发的eABR在评估听觉传导通路的功能方面更加稳定和敏感。从eⅤ潜伏期来看,上脑干通路的发育可能更容易受到长期耳聋的影响

原始出处:

Li Chen, Jun-Ge Zhang, Jing-Wu Sun et al. Electrically evoked auditory brainstem responses to electrical stimulation at round window membrane in congenitally deaf children at different ages. Int J Pediatr Otorhinolaryngol. Jun 2021

 

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    2022-05-16 feather89
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    2021-07-10 8242649

    很有意思

    0

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