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JAMA:是否应该筛查卵巢癌?看权威解答!

2018-02-18 MedSci MedSci原创

卵巢癌是美国妇女中癌症死亡的第五大常见原因,每年约有14000人死亡;其也是导致妇科癌症死亡的主要原因。超过95%的卵巢癌死亡发生在45岁及以上的女性中。近期,发表在权威杂志JAMA上的文章更新了2012年美国预防服务工作组(USPSTF)关于筛查卵巢癌的建议。USPSTF审查了不知卵巢癌高风险(高风险妇女包括患有某些遗传性癌症综合征增加卵巢癌风险的人群)的无症状妇女筛查卵巢癌的益处和危害。研究的

卵巢癌是美国妇女中癌症死亡的第五大常见原因,每年约有14000人死亡;其也是导致妇科癌症死亡的主要原因。超过95%的卵巢癌死亡发生在45岁及以上的女性中。近期,发表在权威杂志JAMA上的文章更新了2012年美国预防服务工作组(USPSTF)关于筛查卵巢癌的建议。USPSTF审查了不知卵巢癌高风险(高风险妇女包括患有某些遗传性癌症综合征增加卵巢癌风险的人群)的无症状妇女筛查卵巢癌的益处和危害。研究的结局包括卵巢癌死亡率、生活质量、假阳性率、手术和手术并发症发生率以及筛查的心理影响。USPSTF发现充分的证据表明,筛查卵巢癌并不能降低卵巢癌死亡率。 USPSTF发现充分的证据表明,筛查卵巢癌的危害至少为中等程度,并且在某些情况下可能很大,并且包括对没有癌症的女性进行不必要的手术。鉴于筛查没有死亡率的益处,以及由于假阳性筛查试验结果和随后的手术可能导致的中度至重大危害,USPSTF以中度确定性得出结论,筛查卵巢癌的危害大于益处,而筛查的益处和危害的净平衡是负的。USPSTF建议不要筛查无症状女性的卵巢癌。(D建议)该建议适用于无症状的不知道患有高风险的遗传性癌症综合征女性。原始出处:US P

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1803781, encodeId=b3d31803e8171, content=<a href='/topic/show?id=ffdbe5926f5' target=_blank style='color:#2F92EE;'>#筛查卵巢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75926, encryptionId=ffdbe5926f5, topicName=筛查卵巢)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sun Jul 01 23:29:00 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289134, encodeId=2f2b28913453, content=筛查就牵涉到经济学的问题.对于卵巢癌还不成熟., beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Mon Feb 19 09:28:19 CST 2018, time=2018-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288977, encodeId=05902889e770, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Feb 18 18:42:28 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288948, encodeId=d2cd288948c1, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sun Feb 18 17:08:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288921, encodeId=356928892173, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun Feb 18 12:25:39 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288910, encodeId=002a28891006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Feb 18 12:09:06 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-02-19 15121100f4m

    筛查就牵涉到经济学的问题.对于卵巢癌还不成熟.

    0

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    2018-02-18 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1803781, encodeId=b3d31803e8171, content=<a href='/topic/show?id=ffdbe5926f5' target=_blank style='color:#2F92EE;'>#筛查卵巢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75926, encryptionId=ffdbe5926f5, topicName=筛查卵巢)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sun Jul 01 23:29:00 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289134, encodeId=2f2b28913453, content=筛查就牵涉到经济学的问题.对于卵巢癌还不成熟., beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Mon Feb 19 09:28:19 CST 2018, time=2018-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288977, encodeId=05902889e770, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Feb 18 18:42:28 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288948, encodeId=d2cd288948c1, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sun Feb 18 17:08:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288921, encodeId=356928892173, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun Feb 18 12:25:39 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288910, encodeId=002a28891006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Feb 18 12:09:06 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-02-18 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

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    2018-02-18 wqkm

    ^_^^_^^_^

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1803781, encodeId=b3d31803e8171, content=<a href='/topic/show?id=ffdbe5926f5' target=_blank style='color:#2F92EE;'>#筛查卵巢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75926, encryptionId=ffdbe5926f5, topicName=筛查卵巢)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sun Jul 01 23:29:00 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289134, encodeId=2f2b28913453, content=筛查就牵涉到经济学的问题.对于卵巢癌还不成熟., beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Mon Feb 19 09:28:19 CST 2018, time=2018-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288977, encodeId=05902889e770, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Feb 18 18:42:28 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288948, encodeId=d2cd288948c1, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sun Feb 18 17:08:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288921, encodeId=356928892173, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun Feb 18 12:25:39 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288910, encodeId=002a28891006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Feb 18 12:09:06 CST 2018, time=2018-02-18, status=1, ipAttribution=)]
    2018-02-18 1ddf0692m34(暂无匿称)

    学习了,涨知识

    0

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