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JACC:心脏移植后恶性肿瘤的发生风险明显增高!

2018-01-04 MedSci MedSci原创

恶性肿瘤的发生是接受心脏移植治疗患者的重要并发症之一。本研究的目的旨在评估心脏移植患者恶性肿瘤的发生率、类型以及预测因素。本研究纳入了17587名仅接受了心脏移植的成年人,主要终点事件是新发恶性肿瘤的发生、类型以及出现时间。结果发现,接受心脏移植后的1-5年,新发恶性实体肿瘤的发生率为10.7%,主要类型有:皮肤癌(7%)、非皮肤实体癌(4%)和淋巴组织增生性疾病(0.9%)。各类型肿瘤的发生时间

恶性肿瘤的发生是接受心脏移植治疗患者的重要并发症之一。本研究的目的旨在评估心脏移植患者恶性肿瘤的发生率、类型以及预测因素。

本研究纳入了17587名仅接受了心脏移植的成年人,主要终点事件是新发恶性肿瘤的发生、类型以及出现时间。结果发现,接受心脏移植后的1-5年,新发恶性实体肿瘤的发生率为10.7%,主要类型有:皮肤癌(7%)、非皮肤实体癌(4%)和淋巴组织增生性疾病(0.9%)。各类型肿瘤的发生时间无明显差异。然而,新发恶性肿瘤的发生率从2000-2005年的10%上升至2006-2011年的12.4%(p < 0.0001)。出现有新发恶性肿瘤的患者生存率要明显低于无新发恶性肿瘤患者(p < 0.0001)。

研究结果显示,有超过10%的接受心脏移植患者在术后1-5年出现有新发恶性肿瘤,并且与死亡率的增加呈相关性。

原始出处:


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    2018-12-13 hbwxf
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    2018-01-06 liuxiaona
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    2018-01-06 liuxiaona
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    2018-01-05 owlhealth

    学习了.不错

    0

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    2018-01-05 owlhealth

    学习了

    0

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