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SCI REP：阿兹海默症竟是肺癌“克星”，科学家找到治疗肺癌新线索！

2017-07-04 佚名 medicalxpress 

阿兹海默症肺癌治疗线索
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阿尔茨海默氏症患者患胶质母细胞瘤的风险增加，而患肺癌的风险却降低。一份来自西班牙国家癌症研究中心(CNIO)研究报告描述了这个疾病的生物过程

阿尔茨海默氏症患者患胶质母细胞瘤的风险增加，而患肺癌的风险却降低。一份来自西班牙国家癌症研究中心(CNIO)研究报告描述了这个疾病的生物过程。预期寿命潜在增加了人们患多种疾病的风险，一种疾病与另一种疾病存在着各种关系，有时候一种疾病可以增加其他疾病的风险，然而有时，两种疾病之间却成反比关系。流行病学已经确定了很多疾病之间的关系，如某些中枢神经系统疾病会降低某些癌症的发生率。早在2014年发表的一篇论文中，研究人员就已经指出中枢神经系统疾病，如阿尔茨海默氏症，帕金森氏症和精神分裂症都会降低是某些癌症的发病率，如肺癌，结肠癌和前列腺癌等，反之亦然。理解这些分子的过程为每种疾病的成因提供了重要的信息，为全新治疗方法的开发提供了新的可能性。近期，一篇发表在《科学报告》中的研究深入探究了阿尔茨海默病和脑部肿瘤以及肺癌之间的关系。研究人员表示：“胶质母细胞瘤与阿尔茨海默氏症起源于相同的器官，这使我们可以更好地理解阿尔茨海默氏症和癌症的疾病分子。”在研究过程中，科学家分析1000多名患者的样本，并确定了198个改变显着的基因功能。其中，112个在阿尔茨海默病和胶质母细胞瘤中都具有类似的模式，而在肺癌

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1465345, encodeId=36431465345fc, content=<a href='/topic/show?id=78829e719a0' target=_blank style='color:#2F92EE;'>#阿兹海默症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97719, encryptionId=78829e719a0, topicName=阿兹海默症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8e96710983, createdName=jiekemin, createdTime=Thu Jul 06 00:09:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218724, encodeId=7720218e242b, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Jul 05 07:38:38 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218506, encodeId=3ac8218506b2, content=非常好的文章，学习了，很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jul 04 13:26:17 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218475, encodeId=b9102184e5f4, content=阿尔茨海默氏症患者患胶质母细胞瘤的风险增加，而患肺癌的风险却降低。一份来自西班牙国家癌症研究中心(CNIO)研究报告描述了这个疾病的生物过程。, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Tue Jul 04 11:12:22 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218467, encodeId=821a21846eea, content=很好学习来感兴趣的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Tue Jul 04 10:18:51 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218455, encodeId=78f321845592, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Tue Jul 04 09:57:23 CST 2017, time=2017-07-04, status=1, ipAttribution=)]
    2017-07-06 jiekemin

    #阿兹海默症#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1465345, encodeId=36431465345fc, content=<a href='/topic/show?id=78829e719a0' target=_blank style='color:#2F92EE;'>#阿兹海默症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97719, encryptionId=78829e719a0, topicName=阿兹海默症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8e96710983, createdName=jiekemin, createdTime=Thu Jul 06 00:09:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218724, encodeId=7720218e242b, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Jul 05 07:38:38 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218506, encodeId=3ac8218506b2, content=非常好的文章，学习了，很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jul 04 13:26:17 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218475, encodeId=b9102184e5f4, content=阿尔茨海默氏症患者患胶质母细胞瘤的风险增加，而患肺癌的风险却降低。一份来自西班牙国家癌症研究中心(CNIO)研究报告描述了这个疾病的生物过程。, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Tue Jul 04 11:12:22 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218467, encodeId=821a21846eea, content=很好学习来感兴趣的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Tue Jul 04 10:18:51 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218455, encodeId=78f321845592, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Tue Jul 04 09:57:23 CST 2017, time=2017-07-04, status=1, ipAttribution=)]
    2017-07-05 ylzr123

    认真学习，不断进步，把经验分享给同好。点赞了！

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1465345, encodeId=36431465345fc, content=<a href='/topic/show?id=78829e719a0' target=_blank style='color:#2F92EE;'>#阿兹海默症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97719, encryptionId=78829e719a0, topicName=阿兹海默症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8e96710983, createdName=jiekemin, createdTime=Thu Jul 06 00:09:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218724, encodeId=7720218e242b, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Jul 05 07:38:38 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218506, encodeId=3ac8218506b2, content=非常好的文章，学习了，很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jul 04 13:26:17 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218475, encodeId=b9102184e5f4, content=阿尔茨海默氏症患者患胶质母细胞瘤的风险增加，而患肺癌的风险却降低。一份来自西班牙国家癌症研究中心(CNIO)研究报告描述了这个疾病的生物过程。, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Tue Jul 04 11:12:22 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218467, encodeId=821a21846eea, content=很好学习来感兴趣的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Tue Jul 04 10:18:51 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218455, encodeId=78f321845592, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Tue Jul 04 09:57:23 CST 2017, time=2017-07-04, status=1, ipAttribution=)]
    2017-07-04 天涯183

    非常好的文章，学习了，很受益

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1465345, encodeId=36431465345fc, content=<a href='/topic/show?id=78829e719a0' target=_blank style='color:#2F92EE;'>#阿兹海默症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97719, encryptionId=78829e719a0, topicName=阿兹海默症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8e96710983, createdName=jiekemin, createdTime=Thu Jul 06 00:09:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218724, encodeId=7720218e242b, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Jul 05 07:38:38 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218506, encodeId=3ac8218506b2, content=非常好的文章，学习了，很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jul 04 13:26:17 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218475, encodeId=b9102184e5f4, content=阿尔茨海默氏症患者患胶质母细胞瘤的风险增加，而患肺癌的风险却降低。一份来自西班牙国家癌症研究中心(CNIO)研究报告描述了这个疾病的生物过程。, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Tue Jul 04 11:12:22 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218467, encodeId=821a21846eea, content=很好学习来感兴趣的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Tue Jul 04 10:18:51 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218455, encodeId=78f321845592, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Tue Jul 04 09:57:23 CST 2017, time=2017-07-04, status=1, ipAttribution=)]
    2017-07-04 Julie W

    阿尔茨海默氏症患者患胶质母细胞瘤的风险增加，而患肺癌的风险却降低。一份来自西班牙国家癌症研究中心(CNIO)研究报告描述了这个疾病的生物过程。

    0

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    2017-07-04 zwjnj2

    很好学习来感兴趣的问题

    0

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    2017-07-04 楠博One

    学习谢谢分享

    0

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