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Pediatrics:贫困和交通不便捷也增加药物不依从性

2018-05-04 易湛苗 环球医学网

发表在《Pediatrics》的一项由美国科学家进行的研究,考察了贫困、交通便捷性对药物不依从性的影响。

发表在《Pediatrics》的一项由美国科学家进行的研究,考察了贫困、交通便捷性对药物不依从性的影响。

背景和目的:原发性药物不依从性(PMN)或未能再次取药的差异,可影响阶级差距并扩大公平差距。本研究旨在评估1个都市区的PMN,并评估其与潜在邮政编码差异的相关性。

方法:这是一项回顾性观察性研究,数据采自于1个区域性社区药房市场份额领导者(2016年10月~2017年4月)。数据包含患者年龄、性别、支付者、药物类型和家庭邮政编码。邮政编码与美国人口普查测量列举的贫困和交通便捷性相连,并作为连续变量和在五分位数内处理。处方水平的结局为处方是否在到达药房的30天内再次取药。生态水平的结局为每个邮政编码计算得出的PMN(分子为未再次取药;分母为再次取药)。

结果:纳入的54家药房共收到213719个处方;12.2%未再次取药。年龄较大的儿童、男孩和有公共保险的人更可能未再次取药。来自于最高贫困五分位数的处方比来自于最低贫困五分位数的处方显着更可能未再次取药(校正比值比[OR] 1.60;95% 置信区间[CI] 1.52~1.69);交通便捷性也具有相似的模式(校正OR 1.77;95% CI 1.68~1.87)。在生态水平,PMN率与贫困及交通便捷性之间具有显着的等级相关性(P都<0.0001);这些梯度延伸至所有药物类别。

结论:在1个都市区,贫困和交通便捷性与处方水平和生态水平PMN的显着差异相关。药师和药房在人口健康的努力中很关键。

原始出处:
Hensley C, Heaton PC, Kahn RS, et al.Poverty, Transportation Access, and Medication Nonadherence.Pediatrics. 2018 Apr;141(4). pii: e20173402. doi: 10.1542/peds.2017-3402. Epub 2018 Mar 16.

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    2019-04-07 feather89
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    2018-10-22 hbwxf
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    2018-05-06 fyxzlh
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    2018-05-06 yuandd
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    2018-05-04 神功盖世

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