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Prostate Cancer P D:前列腺癌诊断后自杀的发生率和风险因子

2018-09-01 AlexYang MedSci原创

是否前列腺癌的诊断在男性中造成心理压力从而引起自杀,仍旧存在争议。最近,有研究人员对之前的研究进行了元分析来调查前列腺癌诊断男性的自杀的发生率和相关的风险因子。研究发现,8个观察性研究总共包括了1281393名诊断为前列腺癌的男性,并且包括了842294名匹配的无前列腺癌的男性对照。在前列腺癌诊断的第一年,总的增加的自杀相对风险(RR)为2.01(95% CI: 1.52-2.64; P<0

是否前列腺癌的诊断在男性中造成心理压力从而引起自杀,仍旧存在争议。最近,有研究人员对之前的研究进行了元分析来调查前列腺癌诊断男性的自杀的发生率和相关的风险因子。

研究发现,8个观察性研究总共包括了1281393名诊断为前列腺癌的男性,并且包括了842294名匹配的无前列腺癌的男性对照。在前列腺癌诊断的第一年,总的增加的自杀相对风险(RR)为2.01(95% CI: 1.52-2.64; P<0.001; I2=91.8%),而在诊断后首6个月中更加严重(RR=2.24, 95% CI: 1.77-2.85; P<0.001; I2=61.1%)。更多的是,在年龄75岁及以上的前列腺癌男性患者(RR=1.51, 95% CI: 1.04-2.18; P=0.028; I2=91.5%)和激素治疗的男性患者(RR=1.80, 95% CI: 1.54-2.12; P<0.001; I2=0%)中自杀风险增加。进一步的是,婚姻状况、种族、疾病风险类别和社会经济状况在男性前列腺癌患者自杀风险中是没有相关性的。

最后,研究人员指出,目前的证据表明了自杀的风险在诊断为前列腺癌的男性患者中是增加的,尤其是年量不小于75岁和诊断12个月之内以及激素治疗的男性。因此,健康护理工作者因该警惕这些特殊人群的高风险自杀情况。

原始出处:

Zhenlang Guo, Shu Gan, Yuan Li et al. Incidence and risk factors of suicide after a prostate cancer diagnosis: a meta-analysis of observational studies. Prostate Cancer P D. 14 Aug 2018.

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    2018-09-09 xiaotao112411

    学习学习学习

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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:40 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344128, encodeId=a7743441280f, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:37 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344127, encodeId=d05134412e23, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:33 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 xiaotao112411

    学习学习学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1826474, encodeId=ac0a18264e4d9, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Jul 05 14:33:00 CST 2019, time=2019-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1791543, encodeId=475f1e91543c7, content=<a href='/topic/show?id=b77f14e4541' target=_blank style='color:#2F92EE;'>#Prostate Ca#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14745, encryptionId=b77f14e4541, topicName=Prostate Ca)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Fri Jun 21 22:33:00 CST 2019, time=2019-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344134, encodeId=f89e34413432, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:57 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344133, encodeId=03cc34413344, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:40 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344128, encodeId=a7743441280f, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:37 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344127, encodeId=d05134412e23, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:33 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 xiaotao112411

    学习学习学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1826474, encodeId=ac0a18264e4d9, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Jul 05 14:33:00 CST 2019, time=2019-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1791543, encodeId=475f1e91543c7, content=<a href='/topic/show?id=b77f14e4541' target=_blank style='color:#2F92EE;'>#Prostate Ca#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14745, encryptionId=b77f14e4541, topicName=Prostate Ca)], attachment=null, authenticateStatus=null, createdAvatar=, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:40 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344128, encodeId=a7743441280f, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:37 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344127, encodeId=d05134412e23, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:33 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 xiaotao112411

    学习学习学习

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:33 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 xiaotao112411

    学习学习学习

    0

  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:40 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344128, encodeId=a7743441280f, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:37 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344127, encodeId=d05134412e23, content= 学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:33 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 xiaotao112411

    学习学习学习

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:33 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 xiaotao112411

    学习学习学习

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Sep 09 08:59:33 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 xiaotao112411

    学习学习学习

    0

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