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Am J Gastroenterol:早期穿刺术可改善新发肝硬化腹水住院患者再入院

2016-01-25 徐媛 MedSci原创

肝硬化腹水的诊断与发病率,死亡率,和减少健康相关的生活质量具有相关性,通过质量指标(QIs)可以降低患者再入院率和死亡率。研究人员通过质量指标来评估对因腹水住院的患者的治疗质量。 研究人员收纳了302名新发肝硬化腹水住院患者,并记录了入院治疗的相关临床数据,分析了患者腹水诊断30天再紧急入院的入院率和90天死亡率。 研究发现,大部分患者为男性(68.9%),年龄均超过50岁(年龄57±12.8

肝硬化腹水的诊断与发病率,死亡率,和减少健康相关的生活质量具有相关性,通过质量指标(QIs)可以降低患者再入院率和死亡率。研究人员通过质量指标来评估对因腹水住院的患者的治疗质量。

研究人员收纳了302名新发肝硬化腹水住院患者,并记录了入院治疗的相关临床数据,分析了患者腹水诊断30天再紧急入院的入院率和90天死亡率。

研究发现,大部分患者为男性(68.9%),年龄均超过50岁(年龄57±12.83 岁),其中有59%为酒精性肝硬化患者。29%的患者在30天内再次入院。30天紧急再入院率的相对风险在确诊30天内(RR 0.41,P=0.004)或住院期间(RR 0.57,P=0.006)接受腹部穿刺的患者中显著较低。90天的死亡率的独立预测因子包括年龄(OR 1.03,P = 0.03),增加了终末期肝病模型(MELD)-Na分数(OR 1.06,P = 1.06),主要SBP预防(QI7,OR 2.30,P = 2.30)和30天再入院(OR 30.26,P < 0.001)。利尿剂处方的应用会降低90天死亡率(OR 0.28,P=0.01)。71%的患者因复发性腹水在90天内再入院。总体死亡率为46%,30天再入院率是90天死亡率的一个重要预测因素。

研究结论,早期穿刺术对新发肝硬化腹水住院患者可降低30天内再入院,早期开始利尿剂治疗降低了90天的死亡率。

原始出处

Le S1,2, Spelman T3, Chong CP4, Ha P2, Sahhar L2, Lim J2, He T2, Heerasing N4, Sievert W1,2.Could Adherence to Quality of Care Indicators for Hospitalized Patients With Cirrhosis-Related Ascites Improve Clinical Outcomes?Am J Gastroenterol. 2016 Jan;

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    2016-09-20 许安
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    2016-01-27 rgjl
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    2016-01-25 Channel J

    良好的对症治疗

    0

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    2016-01-25 xiaoju

    可以学习一下

    0

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