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葡萄柚籽提取物和木糖醇Xlear可杀死和/或灭活SARS-CoV-2 可有效抵御新的变异病毒

2021-01-28 国际文传 国际文传

Xlear的成分(葡萄柚籽提取物和木糖醇)可显著杀灭COVID-19致病病毒SARS-CoV-2

犹他州立大学和西北大学合作完成的一项新的体外研究发现,Xlear的成分(葡萄柚籽提取物和木糖醇)可显著杀灭COVID-19致病病毒SARS-CoV-2。影像学研究部分是在西北大学NUANCE中心BioCryo实验室开展的。

该研究对使用单一浓度Xlear鼻腔喷雾剂后的SARS-CoV-2病毒滴度和LRV进行了测试。研究显示,“接触时间25分钟后,鼻腔喷雾剂将病毒从4.2 log10 CCID50/0.1 mL降至1.7 log10 CCID50/0.1 mL,降幅为2.5 log10 CCID50/0.1 mL,差异(P<0.001)具有统计学意义。”西北大学/犹他州立大学的这项研究是一系列研究中的最新研究,结论是Xlear可有效抵御SARS-CoV-2。

不过,该研究在两个重要方面实现新突破,西北大学费恩伯格医学院教授Mark Cannon博士表示:“首先,我们的结论是,除了抵御SARS-CoV-2,Xlear还可能有效防止未来的H1N1病毒的传播,包括新发的SARS-CoV-2变异病毒,以及其他病毒性流行病。鉴于我们现在面临的变异病毒传播性更强,该结论至关重要。其次,使用电子显微镜,我们有视觉证据显示,木糖醇和GSE能够抵御该病毒。GSE可杀死病毒,而木糖醇可阻止病毒附着于细胞壁。附图显示,SARS-CoV-2病毒位于细胞外侧且从未附着,感染因此得以阻止。”该研究假设,木糖醇作为SARS-CoV-2的诱饵目标,阻止病毒附着于细胞壁上的核心蛋白。

此次协作研究得出的结论是:“由于使用X/GSE组合疗法不存在危险因素,[Xlear]鼻腔喷雾剂无需处方即可在柜台出售,且[Xlear]不影响长时间舒适地佩戴口罩,因此应鼓励采纳这种预防性的抗病毒治疗。”

研究全文:https://www.biorxiv.org/content/10.1101/2020.12.02.408575v3.full

阅读原文:http://www.businesswirechina.com/zh/news/45604.html

 

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    2021-07-19 hukaixun
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    2021-01-30 小刀医生
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    2021-01-29 T2DM终结者

    有点神奇

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