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Clin Oral Investig:牙周手术之后,使用盐水漱口可以促进创口愈合

2021-10-11 MedSci原创 MedSci原创

牙周病是最常见的口腔疾病之一,漱口水常用于其治疗或治疗效果的维持。洗必泰是全球研究最多的抗菌剂,在临床上被广泛使用,然而其常见副作用较多。近日,发表于Clin Oral Investig的一项随机研究

牙周病是最常见的口腔疾病之一,漱口水常用于其治疗或治疗效果的维持。洗必泰是全球研究最多的抗菌剂,在临床上被广泛使用,然而其常见副作用较多。近日,发表于Clin Oral Investig的一项随机研究比较了氯酸钠和0.12%洗必泰漱口液对接受牙周微创手术患者的抗炎效果。

研究人员随机选择了47名诊断为牙周炎并有入路翻瓣手术指征的患者。A组:术后使用氯化钠(盐)水基漱口水(试验组)或B组:0.12%洗必泰漱口水(对照组)。在基线(T1)、一周后(T2)和治疗后12周(T3)对全口和手术部位的牙龈指数(GI)进行评估。使用商业试剂盒和平板阅读器测量GCF中的总MMP活性。使用Friedman测试和Wilcoxon签名排名测试比较了T1与T2、T1与T3、T2与T3时间间隔的总MMP活性和GI的中位数,还使用Mann-WhitneyU测试比较了每个时间点的试验和对照。

 

结果显示,测试组的平均GI值在基线与T2(P = 0.0005)和基线与T3(P = 0.003)之间显示出明显的差异。而在每个时间点,试验组和对照组之间没有发现明显的差异(所有-值>0.10)。在术后疼痛值方面,试验组和对照组之间的P值为0.58,表明两组之间同样没有明显差异。

综上所述,该研究结果表明,在微创牙周手术后,使用盐水漱口水显示出与CHX 0.12%相似的抗炎效果。盐水是世界人民都可以使用的漱口水,并可促进牙周手术后的创口愈合过程。

 

原始出处:

 

James Rudolph Collins, et al., Anti-inflammatory effect of salt water and chlorhexidine 0.12% mouthrinse after periodontal surgery: a randomized prospective clinical study. Clin Oral Investig. 2021 Jul;25(7):4349-4357. doi: 10.1007/s00784-020-03748-w. 

 

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    2022-07-01 小几洁
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    2021-10-12 weigq

    👍

    0

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    2021-10-11 Jenny6666

    盐水浓度多少啊?

    0

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