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Int J Cardiol:1型和2型糖尿病与7种心血管疾病的发病率!

2018-03-24 xing.T MedSci原创

由此可见,T1DM和T2DM与主要CVD结局风险增加有关。

1型糖尿病(T1DM)与特定心血管疾病(CVD)之间的关联尚不确定。此外,2型糖尿病(T2DM)与主动脉瓣狭窄、房颤、腹主动脉瘤和脑内出血风险之间的数据很少,也不确定。近日,心血管领域权威杂志International Journal of Cardiology上发表了一篇研究文章,研究人员评估了T1DM和T2DM与7种CVD结局之间的相关性。

这项研究包括了来自两个基于人群的前瞻性队列的71483名瑞典成人。研究人员通过与基于人群的登记中心进行联系确定了T1DM和T2DM诊断和CVD的发生率。

T1DM与心肌梗死(风险比[HR]为3.26; 95%可信区间[CI]为2.47-4.30)、心力衰竭(HR为2.68; 95%CI为1.76-4.09)和缺血性卒中(HR为2.61; 95%CI为1.80-3.79)相关。在2型糖尿病患者中也观察到心肌梗死、缺血性卒中和心力衰竭的风险增加,并且伴随着T2DM病程增长,这种相关性程度有所增加。T2DM也与主动脉瓣狭窄风险增加有关(HR为1.34; 95%CI为1.05-1.71),同时也与腹主动脉瘤(HR为0.57; 95%CI为0.40-0.82)和脑出血(HR为0.51; 95%CI为0.30-0.88)风险降低相关。只有较长病程的T2DM(≥20年)与房颤风险增加有关(HR为1.44; 95%CI为1.02-2.04)。

由此可见,T1DM和T2DM与主要CVD结局风险增加有关。

原始出处:

Susanna C. Larsson,et al. Type 1 and type 2 diabetes mellitus and incidence of seven cardiovascular diseases.International Journal of Cardiology.2018. https://doi.org/10.1016/j.ijcard.2018.03.099

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