Baidu
map

药械

订阅

MedSci主页 / 所有栏目 / 药械

广谱抗病毒抑制剂研究进展

2014-01-03 王程玉,王晓佳 生物化学与生物物理学进展

广谱抗病毒制剂病毒入侵感染细胞防御
关注

 研制广谱抗病毒制剂是病毒学前瞻性方向，也是国际医药界倍受瞩目的热点之一．近年来，广谱抗病毒制剂相关研究 获得长足进展，突破了抗病毒制剂单一宿主的瓶颈与限制，以及广谱类制剂活性相对较弱的原有思维，部分成果已面向临床应用．本文基于病毒侵染以及宿主细胞防 御两个层面，全面综述新型广谱抗病毒抑制剂的研究进展与应用潜力，讨论现存的挑战，并展望了未来研究趋势广谱抗病毒抑制剂研究进展.pdf

 研制广谱抗病毒制剂是病毒学前瞻性方向，也是国际医药界倍受瞩目的热点之一．近年来，广谱抗病毒制剂相关研究 获得长足进展，突破了抗病毒制剂单一宿主的瓶颈与限制，以及广谱类制剂活性相对较弱的原有思维，部分成果已面向临床应用．本文基于病毒侵染以及宿主细胞防 御两个层面，全面综述新型广谱抗病毒抑制剂的研究进展与应用潜力，讨论现存的挑战，并展望了未来研究趋势
广谱抗病毒抑制剂研究进展.pdf

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2007018, encodeId=9c2a200e018bb, content=<a href='/topic/show?id=9d62e0946c6' target=_blank style='color:#2F92EE;'>#病毒抑制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70946, encryptionId=9d62e0946c6, topicName=病毒抑制)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Thu Sep 11 16:50:00 CST 2014, time=2014-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1851150, encodeId=09be18511507a, content=<a href='/topic/show?id=f0a254918f0' target=_blank style='color:#2F92EE;'>#抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54918, encryptionId=f0a254918f0, topicName=抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Sat Jan 11 04:50:00 CST 2014, time=2014-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957092, encodeId=79cc195e092f5, content=<a href='/topic/show?id=a8d5e09475e' target=_blank style='color:#2F92EE;'>#病毒抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70947, encryptionId=a8d5e09475e, topicName=病毒抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Mon Mar 03 08:50:00 CST 2014, time=2014-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292305, encodeId=8e5f129230580, content=<a href='/topic/show?id=a3b4554e19d' target=_blank style='color:#2F92EE;'>#抗病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55471, encryptionId=a3b4554e19d, topicName=抗病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1380403, encodeId=8af813804039f, content=<a href='/topic/show?id=9281e34519b' target=_blank style='color:#2F92EE;'>#研究进展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73451, encryptionId=9281e34519b, topicName=研究进展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f13d475, createdName=mashirong, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=)]
    2014-09-11 siiner

    #病毒抑制#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2007018, encodeId=9c2a200e018bb, content=<a href='/topic/show?id=9d62e0946c6' target=_blank style='color:#2F92EE;'>#病毒抑制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70946, encryptionId=9d62e0946c6, topicName=病毒抑制)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Thu Sep 11 16:50:00 CST 2014, time=2014-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1851150, encodeId=09be18511507a, content=<a href='/topic/show?id=f0a254918f0' target=_blank style='color:#2F92EE;'>#抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54918, encryptionId=f0a254918f0, topicName=抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Sat Jan 11 04:50:00 CST 2014, time=2014-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957092, encodeId=79cc195e092f5, content=<a href='/topic/show?id=a8d5e09475e' target=_blank style='color:#2F92EE;'>#病毒抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70947, encryptionId=a8d5e09475e, topicName=病毒抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Mon Mar 03 08:50:00 CST 2014, time=2014-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292305, encodeId=8e5f129230580, content=<a href='/topic/show?id=a3b4554e19d' target=_blank style='color:#2F92EE;'>#抗病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55471, encryptionId=a3b4554e19d, topicName=抗病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1380403, encodeId=8af813804039f, content=<a href='/topic/show?id=9281e34519b' target=_blank style='color:#2F92EE;'>#研究进展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73451, encryptionId=9281e34519b, topicName=研究进展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f13d475, createdName=mashirong, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=)]
    2014-01-11 jklm09

    #抑制剂#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2007018, encodeId=9c2a200e018bb, content=<a href='/topic/show?id=9d62e0946c6' target=_blank style='color:#2F92EE;'>#病毒抑制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70946, encryptionId=9d62e0946c6, topicName=病毒抑制)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Thu Sep 11 16:50:00 CST 2014, time=2014-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1851150, encodeId=09be18511507a, content=<a href='/topic/show?id=f0a254918f0' target=_blank style='color:#2F92EE;'>#抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54918, encryptionId=f0a254918f0, topicName=抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Sat Jan 11 04:50:00 CST 2014, time=2014-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957092, encodeId=79cc195e092f5, content=<a href='/topic/show?id=a8d5e09475e' target=_blank style='color:#2F92EE;'>#病毒抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70947, encryptionId=a8d5e09475e, topicName=病毒抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Mon Mar 03 08:50:00 CST 2014, time=2014-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292305, encodeId=8e5f129230580, content=<a href='/topic/show?id=a3b4554e19d' target=_blank style='color:#2F92EE;'>#抗病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55471, encryptionId=a3b4554e19d, topicName=抗病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1380403, encodeId=8af813804039f, content=<a href='/topic/show?id=9281e34519b' target=_blank style='color:#2F92EE;'>#研究进展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73451, encryptionId=9281e34519b, topicName=研究进展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f13d475, createdName=mashirong, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=)]
    2014-03-03 若水123

    #病毒抑制剂#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2007018, encodeId=9c2a200e018bb, content=<a href='/topic/show?id=9d62e0946c6' target=_blank style='color:#2F92EE;'>#病毒抑制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70946, encryptionId=9d62e0946c6, topicName=病毒抑制)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Thu Sep 11 16:50:00 CST 2014, time=2014-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1851150, encodeId=09be18511507a, content=<a href='/topic/show?id=f0a254918f0' target=_blank style='color:#2F92EE;'>#抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54918, encryptionId=f0a254918f0, topicName=抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Sat Jan 11 04:50:00 CST 2014, time=2014-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957092, encodeId=79cc195e092f5, content=<a href='/topic/show?id=a8d5e09475e' target=_blank style='color:#2F92EE;'>#病毒抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70947, encryptionId=a8d5e09475e, topicName=病毒抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Mon Mar 03 08:50:00 CST 2014, time=2014-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292305, encodeId=8e5f129230580, content=<a href='/topic/show?id=a3b4554e19d' target=_blank style='color:#2F92EE;'>#抗病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55471, encryptionId=a3b4554e19d, topicName=抗病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1380403, encodeId=8af813804039f, content=<a href='/topic/show?id=9281e34519b' target=_blank style='color:#2F92EE;'>#研究进展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73451, encryptionId=9281e34519b, topicName=研究进展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f13d475, createdName=mashirong, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=)]
    2014-01-05 yahu

    #抗病毒#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2007018, encodeId=9c2a200e018bb, content=<a href='/topic/show?id=9d62e0946c6' target=_blank style='color:#2F92EE;'>#病毒抑制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70946, encryptionId=9d62e0946c6, topicName=病毒抑制)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Thu Sep 11 16:50:00 CST 2014, time=2014-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1851150, encodeId=09be18511507a, content=<a href='/topic/show?id=f0a254918f0' target=_blank style='color:#2F92EE;'>#抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54918, encryptionId=f0a254918f0, topicName=抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Sat Jan 11 04:50:00 CST 2014, time=2014-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957092, encodeId=79cc195e092f5, content=<a href='/topic/show?id=a8d5e09475e' target=_blank style='color:#2F92EE;'>#病毒抑制剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70947, encryptionId=a8d5e09475e, topicName=病毒抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Mon Mar 03 08:50:00 CST 2014, time=2014-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292305, encodeId=8e5f129230580, content=<a href='/topic/show?id=a3b4554e19d' target=_blank style='color:#2F92EE;'>#抗病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55471, encryptionId=a3b4554e19d, topicName=抗病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1380403, encodeId=8af813804039f, content=<a href='/topic/show?id=9281e34519b' target=_blank style='color:#2F92EE;'>#研究进展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73451, encryptionId=9281e34519b, topicName=研究进展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f13d475, createdName=mashirong, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=)]
    2014-01-05 mashirong

    #研究进展#

    0

Baidu
map
Baidu
map
Baidu
map