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Am J Psychiatry:揭秘便宜的“抗抑郁药”!(HUNT研究)

2017-10-10 Juka 转化医学网

近年来,抑郁症患者的数量越来越多,伴随着抑郁症的负面消息越来越多,而抑郁症的发病风险也在与日俱增。那么作为一个正常人,如何来防范抑郁症的发生呢?


近年来,抑郁症患者的数量越来越多,伴随着抑郁症的负面消息越来越多,而抑郁症的发病风险也在与日俱增。那么作为一个正常人,如何来防范抑郁症的发生呢?

近日,一项具有里程碑意义的研究发布在美国精神病杂志上。这项由Black Dog Institute领导的研究表示:不论任何年龄,不管是男是女,只要每周进行一个小时的运动,就可以大大的降低抑郁症的发生几率!

这项研究在挪威进行,通过11年对33908挪威的患有焦虑和抑郁症的成年患者的研究发现:

哪怕每周只进行一个小时的运动,可以降低郁郁症风险高达12%!

以前,我们或多或少都知道运动可以排遣过多的抑郁的情绪,也明白运动可以帮助我们减轻心理负担,但是这次大样本的研究告诉我们:预防抑郁症对于我们每个人而言,所需要付出的时间成本和精力原来如此至少。

来自黑狗研究所的Samuel Harvey副教授说道:“在很久以前我们就明白运动在治疗抑郁和焦虑可以通过运动来治疗,但是这是我们第一次去真正的评估运动在抑郁症的预防当中扮演者怎样的角色,而我们确实发现了运动可以降低抑郁症的发病率,这个结果令我们都振奋异常。而我们的发现表明:和抑郁症给我们带来的坏处相比,预防抑郁症需要我们付出的代价甚少!”

而这个研究带给我们的结果却远非如此。Harvey副教授说道:“我们通过这个研究发现了另外一个有趣的事实:每周,我们获得的对于精神方面的益处,大部分都是在活动的第一个小时内获得的。这是个很有趣的事情。”

而目前,研究人员们正在研究运动和精神活动到底存在着什么样的内部联系。研究人员相信精神改善是一个综合效果的呈现,运动和社会同时扮演着重要的角色。

在这项研究中,研究人员使用了Nord-Tr?ndelag县的健康研究数据(HUNT研究),这是1984年1月至1997年6月期间进行的最大、最全面的对于人口的健康状况调查之一。

而在这项调查当中,研究人员发现:

相对于那些每周运动1~2个小时(或者更多)的人,运动时间很少的患抑郁症的风险增加了44%。



研究数据:抑郁症和活动时间的关系

同时这项研究告诉我们:运动并没有很好的证据证明可以帮助我们排解焦虑,同时运动水平和运动强度对于生长发育过程中的障碍也并没有关联。(对这个结果小编采取观望态度。)

定期的休闲娱乐运动可以很好的帮助我们预防抑郁症,这是毋庸置疑的!每周一小时的运动,大概是成本最低的“抗抑郁药”。

原始出处:

Harvey SB, ?verland S, Hatch S.Exercise and the Prevention of Depression: Results of the HUNT Cohort Study.Am J Psychiatry. 2017 Oct 3:appiajp201716111223. doi: 10.1176/appi.ajp.2017.16111223. [Epub ahead of print]

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    2017-10-20 明天会更好!

    继续努力.加油加油

    0

  3. 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    2017-10-15 sunfeifeiyang

    学习

    0

  4. 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08:25:45 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=253030, encodeId=c0382530307a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Oct 15 07:27:21 CST 2017, time=2017-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=252560, encodeId=f7632525602e, content=很好的文章.可以学到很多东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Fri Oct 13 13:52:55 CST 2017, time=2017-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492192, encodeId=853a1492192ea, content=<a href='/topic/show?id=7999553333c' target=_blank style='color:#2F92EE;'>#抗抑郁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55333, encryptionId=7999553333c, topicName=抗抑郁)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a59b8920619, createdName=wushaoling, createdTime=Thu Oct 12 13:23:00 CST 2017, time=2017-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251902, encodeId=1d9d2519025e, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Wed Oct 11 09:37:14 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251893, encodeId=367725189347, content=抑郁症吞噬人的精力.哪还有力气去运动了?, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLJUicgP739INvgkzTYsTUxNjAWx8qDjSzQJibnBH1tkJhsn5LdiaibBCG1dwJI6pLB0EHa3Qjx5ODh8A/0, createdBy=86d82167010, createdName=Anarkia, createdTime=Wed Oct 11 09:03:22 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251890, encodeId=1f2925189072, content=最便宜的抗抑郁药不是阳光吗.晒晒太阳试试, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Wed Oct 11 08:56:33 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251852, encodeId=0c8d25185243, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 11 05:43:53 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251844, encodeId=6787251844ea, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Oct 11 02:43:05 CST 2017, time=2017-10-11, status=1, ipAttribution=)]
    2017-10-13 明天会更好!

    很好的文章.可以学到很多东西

    0

  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Wed Oct 11 08:56:33 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251852, encodeId=0c8d25185243, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 11 05:43:53 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251844, encodeId=6787251844ea, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Oct 11 02:43:05 CST 2017, time=2017-10-11, status=1, ipAttribution=)]
  6. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Wed Oct 11 08:56:33 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251852, encodeId=0c8d25185243, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 11 05:43:53 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251844, encodeId=6787251844ea, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Oct 11 02:43:05 CST 2017, time=2017-10-11, status=1, ipAttribution=)]
    2017-10-11 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

  7. 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likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Oct 11 02:43:05 CST 2017, time=2017-10-11, status=1, ipAttribution=)]
    2017-10-11 Anarkia

    抑郁症吞噬人的精力.哪还有力气去运动了?

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Wed Oct 11 08:56:33 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251852, encodeId=0c8d25185243, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 11 05:43:53 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251844, encodeId=6787251844ea, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Oct 11 02:43:05 CST 2017, time=2017-10-11, status=1, ipAttribution=)]
    2017-10-11 sunfeifeiyang

    最便宜的抗抑郁药不是阳光吗.晒晒太阳试试

    0

  9. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Wed Oct 11 08:56:33 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251852, encodeId=0c8d25185243, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 11 05:43:53 CST 2017, time=2017-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251844, encodeId=6787251844ea, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Oct 11 02:43:05 CST 2017, time=2017-10-11, status=1, ipAttribution=)]
    2017-10-11 yjs木玉

    好好好好好好好好

    0

  10. 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likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Oct 11 02:43:05 CST 2017, time=2017-10-11, status=1, ipAttribution=)]
    2017-10-11 飛歌

    厉害了我的哥

    0

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抑郁症不仅仅是一种心理疾病,它背后同样存在复杂的生理基础。近日,一项来自曼彻斯特大学的研究发现,抑郁症患者的自杀念头与大脑炎症之间存在关联。这是科学家首次在活体中证实这种联系。该研究发表于Biological Psychiatry期刊上。

Sci Rep:研究确定2型糖尿病与抑郁症相关的分子机制

2型糖尿病(T2DM)与抑郁症密切相关,然而,这种关联的确切分子机制是未知的。在这里,研究人员调查了血液中循环RNA(circRNA)是否与T2DM患者抑郁症的发生有关。研究共纳入14例T2DM和抑郁症状的患者。抑郁自评表44分(总粗点)和55分(标准评分)切点定义为抑郁症。使用患者健康问卷9评估常见的精神障碍,评分为5以上的切点为抑郁症。微阵列测定和定量实时逆转录聚合酶链反应显示,与T2DM组相

KK健康:你是抑郁症,还是忧郁情绪?来对号入座吧!

抑郁症是以显著、持续、普遍的抑郁状态为表现形式的一种精神疾病。目前抑郁症是全球第四大疾病负担,也是导致患者功能残疾的主要原因之一,大约有1/7的人会在人生的某个阶段遭受抑郁症困扰。

Transl Psychiatry:食用水产品可降低抑郁症病发率

日本国立癌症研究中心和庆应私塾大学的合作团队于 9 月 27 日在美国的精神病学杂志《Transl Psychiatry》上发表论文称:他们的流行病学调查结果表明,多吃鱼、贝类等水产的人,其抑郁症发病率比一般人小了一半。同时研究还认为,青背类鱼中富含的“ω-3脂肪酸”对预防抑郁症有一定效果。

Am J Psychiatry:每周锻炼一小时就能够有效预防抑郁症发生!

日前,一项刊登在国际杂志American Journal of Psychiatry上的研究报告中,来自黑犬研究所(Black Dog Institute)的研究人员通过研究发现,任何强度的有规律锻炼都能够帮助有效预防未来抑郁症的发生,而且每周仅一个小时的锻炼都能够改变。研究结果表明,甚至很少量的锻炼都能保护机体抵御抑郁症的发生,而且个体的心理健康效益产生与年龄或性别无关。

Biol Psychiat:科学家发现,“神经炎症”是导致抑郁症患者自杀的主要因素

英国曼彻斯特大学(University of Manchester)的一项新研究表明,患有重度抑郁症(MDD)的患者大脑中出现了一种神经胶质激活的标志,这是一种炎症。在这项研究中,彼得·塔尔博特博士和他的同事们发现,炎症标志物的增加,只会在患有MDD的身上出现,因为他们有自杀的想法。将炎症的作用确定在自杀倾向上,而不是诊断MDD本身。

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