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Ann Fam Med:抗生素对儿童临床感染的湿疹无效

2017-03-15 佚名 来宝网

约40%的湿疹采用抗生素治疗,但迪卡夫大学的一项研究表明,口服或局部使用抗生素对儿童临床感染的轻度湿疹无明显疗效。

约40%的湿疹采用抗生素治疗,但迪卡夫大学的一项研究表明,口服或局部使用抗生素对儿童临床感染的轻度湿疹无明显疗效。

湿疹是一种常见病症,儿童多见,英国约有五分之一的儿童感染湿疹。湿疹加重时会出现耀斑,并且皮肤上特定的细菌可能有助于引起这些耀斑。湿疹爆发时常用抗生素治疗,但很少有研究表明抗生素是否具有确切疗效。

CREAM研究旨在了解口服或局部(霜剂或软膏)使用抗生素是否有助于缓解儿童临床感染的严重湿疹,且所有参与儿童同时接受类固醇和润肤剂的标准治疗。

该结果发表在杂志《The Annals of Family Medicine》上,113名非严重感染湿疹儿童分为实验组和对照组,经两周、四周或三个月的治疗后湿疹症状并没有显着差异。

研究人员发现快速自溶对轻度和中等强度的局部皮质类固醇和润肤剂治疗有反应,并排除了口服或局部使用抗生素的临床意义。

卡迪夫大学Nick Francis博士领导的研究表明:局部抗生素联合局部皮质类固醇常用于治疗湿疹爆发。我们的研究表明,即使有感染的迹象,对于儿童较轻的湿疹抗生素作用不大,而且可能引起皮肤过敏。加强局部皮质类固醇和润肤剂的效力应该是临床感染的湿疹爆发治疗的重点。

该研究“儿童临床感染湿疹口服或局部抗生素:门诊治疗中的随机对照试验”发表在杂志《The Annals of Family Medicine》。

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    2017-03-17 1e224f04m83(暂无匿称)

    谢谢老师的分享!

    0

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    2017-03-17 cqykthl

    不一定有感染吧!

    0

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    2017-03-17 laoli

    临床实际很少会全身用的!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=180688, encodeId=e64c180688ec, content=谢谢老师的分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170225/IMG58B132BE210D34905.jpg, createdBy=8c462026466, createdName=1e224f04m83(暂无匿称), createdTime=Fri Mar 17 23:26:06 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180538, encodeId=50af180538b6, content=不一定有感染吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Fri Mar 17 08:35:58 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607303, encodeId=f8dd160e3033b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Mar 17 04:26:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180471, encodeId=207a1804e13a, content=临床实际很少会全身用的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Fri Mar 17 01:06:18 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180222, encodeId=e1a2180222cd, content=这个还用做实验说明吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Mar 16 07:14:04 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180131, encodeId=b770180131f1, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Mar 15 18:54:21 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180096, encodeId=e4fe1800968b, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Mar 15 14:41:27 CST 2017, time=2017-03-15, status=1, ipAttribution=)]
    2017-03-16 stupidox

    这个还用做实验说明吗

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=180688, encodeId=e64c180688ec, content=谢谢老师的分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170225/IMG58B132BE210D34905.jpg, createdBy=8c462026466, createdName=1e224f04m83(暂无匿称), createdTime=Fri Mar 17 23:26:06 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180538, encodeId=50af180538b6, content=不一定有感染吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Fri Mar 17 08:35:58 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607303, encodeId=f8dd160e3033b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Mar 17 04:26:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180471, encodeId=207a1804e13a, content=临床实际很少会全身用的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Fri Mar 17 01:06:18 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180222, encodeId=e1a2180222cd, content=这个还用做实验说明吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Mar 16 07:14:04 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180131, encodeId=b770180131f1, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Mar 15 18:54:21 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180096, encodeId=e4fe1800968b, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Mar 15 14:41:27 CST 2017, time=2017-03-15, status=1, ipAttribution=)]
    2017-03-15 wxl882001

    学习一下

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=180688, encodeId=e64c180688ec, content=谢谢老师的分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170225/IMG58B132BE210D34905.jpg, createdBy=8c462026466, createdName=1e224f04m83(暂无匿称), createdTime=Fri Mar 17 23:26:06 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180538, encodeId=50af180538b6, content=不一定有感染吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Fri Mar 17 08:35:58 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607303, encodeId=f8dd160e3033b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Mar 17 04:26:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180471, encodeId=207a1804e13a, content=临床实际很少会全身用的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Fri Mar 17 01:06:18 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180222, encodeId=e1a2180222cd, content=这个还用做实验说明吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Mar 16 07:14:04 CST 2017, time=2017-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180131, encodeId=b770180131f1, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Wed Mar 15 18:54:21 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180096, encodeId=e4fe1800968b, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Mar 15 14:41:27 CST 2017, time=2017-03-15, status=1, ipAttribution=)]
    2017-03-15 Chongyang Zhang

    签到学习了很多。

    0

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