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女士冠脉介入治疗效果不如男士!JACC汇总分析21项随机研究

2020-04-11 朱朱 中国循环杂志

近期,JACC发表一项包含21项冠脉介入治疗(PCI)随机研究的汇总分析表明,PCI术后5年时,女士中主要不良心血管事件(心原性死亡、心肌梗死、缺血驱动的靶病变血运重建)和缺血驱动的靶病变血运重建发生

近期,JACC发表一项包含21项冠脉介入治疗(PCI)随机研究的汇总分析表明,PCI术后5年时,女士中主要不良心血管事件(心原性死亡、心肌梗死、缺血驱动的靶病变血运重建)和缺血驱动的靶病变血运重建发生风险均高于男士。

这21项研究共纳入32 877例冠心病患者,其中女士占27.8%。

与男士相比,女士年龄较大,体重指数较高,高血压和糖尿病合并比例较高,而既往接受血运重建的比例较低。

冠脉造影数据显示,女士的冠脉病变参考血管直径较小,病变较短。

PCI术后5年时,女士中主要不良心血管事件(18.9% vs. 17.7%)、全因死亡(10.4% vs. 8.7%)、心原性死亡(4.9% vs. 4.0%)、缺血驱动的靶病变血运重建(10.9% vs. 10.2%)发生率均明显高于男士。

多因素分析表明,女性是主要不良心血管事件和缺血驱动的靶病变血运重建的独立预测因素。

PCI术后女士出现主要不良心血管事件和缺血驱动的靶病变血运重建的风险较男士分别增加14%和23%,但全因死亡和心原性死亡风险相似。

来源:Long-Term Outcomes in Women and Men Following Percutaneous Coronary Intervention. J Am Coll Cardiol, 2020, 75(14): 1631-1640.

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    2020-05-16 hbwxf
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    2020-04-11 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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    2020-04-11 肿瘤克星

    高质量研究,读起来真爽,谢谢梅斯

    0

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    2020-04-11 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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