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JAMA Neurol:儿童卒中后血压、血糖和体温与神经系统预后的关系

2016-05-24 MedSci MedSci原创

根据JAMA Neurology在线发表的一篇文章,儿童卒中后梗塞(组织损伤)体积和高血糖症(高血糖)与较差的神经预后相关,但高血压,发烧与结果无关。儿童患者出现动脉缺血性卒中后,对于能够管理血压,血糖水平和温度的最佳管理没有证据为基础的准则。Lori C. Jordan,范德比尔特大学医学中心范德比尔特大学医学中心的医学博士,和其合作者检测了异常血压,血糖水平的患病率和神经学结果的关系。他们对2

根据JAMA Neurology在线发表的一篇文章,儿童卒中后梗塞(组织损伤)体积和高血糖症(高血糖)与较差的神经预后相关,但高血压,发烧与结果无关。


儿童患者出现动脉缺血性卒中后,对于能够管理血压,血糖水平和温度的最佳管理没有证据为基础的准则。

Lori C. Jordan,范德比尔特大学医学中心范德比尔特大学医学中心的医学博士,和其合作者检测了异常血压,血糖水平的患病率和神经学结果的关系。

他们对2009年至2013年间发生第一次动脉缺血性卒中的儿童(平均6岁)进行了一项回顾性研究。该研究共包括98名儿童,研究人员收集了他们卒中五天之后的血压,血糖和温度数据。64例儿童患有高血压,67例儿童患有低血压,17例儿童患有高血糖,37例儿童出现发热。

作者指出,与不良神经系统预后相关性最强的是4%或更大的脑容量损伤梗死面积。根据该结果,高血糖症也与之相关联。然而,高血压,发烧与梗死面积,预后不良或死亡没有显著相关性。

该研究的局限性为血压测量技术。

“还需要更多的前瞻性研究来澄清这些可能改变的生理参数和儿童卒中结果之间的关联,”作者总结道。


原始出处:

Kimberly N. Grelli, Melissa C. Gindville, C. Haley Walker,et al.Association of Blood Pressure, Blood Glucose, and Temperature With Neurological Outcome After Childhood Stroke. JAMA Neurology,2016.5.23

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    2017-03-08 yinhl1978
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    2016-10-14 ylzr123

    好文,值得推荐。

    0

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