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J Clin Periodontol:牙周手术治疗联合抗生素光动力疗法对慢性牙周炎的疗效:一种随机对照临床试验

2017-07-17 MedSci MedSci原创

目的:该随机对照临床试验评估重度慢性牙周炎(SCP)患者手术牙周治疗(ST)辅助单次应用抗微生物光动力治疗(aPDT)的效果。

目的:该随机对照临床试验评估重度慢性牙周炎(SCP)患者手术牙周治疗(ST)辅助单次应用抗微生物光动力治疗(aPDT)的效果。

材料与方法:在半口对照设计中,20例SCP患者接受了aPDT + ST(试验组,TG)或ST(对照组,CG)治疗。 aPDT单独应用一段时间,使用二极管激光和吩噻嗪光敏剂。所有患者均经手术治疗90天。通过棋盘DNA-DNA杂交在第0,60和150天对40个龈下菌种水平进行评估。评估临床和微生物参数。

结果:在深牙周袋(PPD≥5mm)中,试验组在手术治疗90天后,PPD降低显着高于对照组(p <0.05)。试验组牙周致病菌红色复合物(Treponema denticola)明显减少(p <0.05)。

结论:在SCP的外科治疗中,aPDT辅助根面翻瓣术:i)显着改善牙周临床参数; ii)更有效地清除牙周致病菌红色复合物(NCT02734784)。

原始出处:

Sérgio H. L. Martins, Arthur B. Novaes Jr, Mario Taba Jr, et al. Effect of surgical periodontal treatment associated to antimicrobial photodynamic therapy on chronic periodontitis: A randomized controlled clinical trial. Journal of clinical periodontology. 2017 July. doi: 10.1111/jcpe.12744

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    2017-08-17 feather89
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    2018-04-01 amyloid
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    2017-07-23 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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