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怀孕期间压力过大可改变阴道微生物进而影响宝宝的发育

2015-07-09 sunshine 译 MedSci原创

怀孕期间压力过大可改变阴道微生物进而影响宝宝的发育据发表于Endocrinology的一项最新研究表明,母亲怀孕期间压力过大会造成阴道中微生物的变化,可能会影响宝宝的肠道微生物以及宝宝的大脑发育。该研究强调了母亲引导的微生物在宝宝发育过程中的重要性研究人员发现,小鼠在怀孕早期阶段暴露于压力之中可改变其阴道微生物,这将破坏小小鼠的肠道菌群。研究小组还发现,尤其是雄性小小鼠的肠道微生物更易因其母亲阴道

怀孕期间压力过大可改变阴道微生物进而影响宝宝的发育



据发表于Endocrinology的一项最新研究表明,母亲怀孕期间压力过大会造成阴道中微生物的变化,可能会影响宝宝的肠道微生物以及宝宝的大脑发育。

该研究强调了母亲引导的微生物在宝宝发育过程中的重要性

研究人员发现,小鼠在怀孕早期阶段暴露于压力之中可改变其阴道微生物,这将破坏小小鼠的肠道菌群。研究小组还发现,尤其是雄性小小鼠的肠道微生物更易因其母亲阴道微生物的改变而改变。

“母亲在怀孕期间过大的压力可影响其宝宝的发育,包括大脑的发育,其阴道微生物的变化可在分娩时传递给宝宝,”Bale解释道。

“新生儿肠道内的微生物最初是由母亲阴道内的微生物构成的,”她补充道,“孕妇压力过大可改变其阴道微生物的变化,自然改变了新生儿的肠道微生物,同时也确定了宿主免疫系统的很多方面,而这些免疫系统是在建立在人生的早期阶段的。”

研究人员表示他们的发现强调了母亲阴道内微生物在分娩时构成新生儿肠道内微生物的重要性,突出显示了孕妇压力可能在这个重要过程中起到的负面作用。

对于他们的研究成果,Bale说道:

“这些研究具有巨大的转化潜力,很多国家已经对剖腹产的孕妇行口服阴道灌洗以确保婴儿暴露于合适的微生物之中。确定高危人群怀孕期间母亲的经历,尤其是压力是如何改变阴道微生物的至关重要。”

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1824604, encodeId=ef51182460413, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Mon Sep 14 10:34:00 CST 2015, time=2015-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32478, encodeId=eafc324e8dd, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=205, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun Jul 12 16:44:00 CST 2015, time=2015-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347052, encodeId=d1a5134e052a5, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Sat Jul 11 06:34:00 CST 2015, time=2015-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32232, encodeId=8a9732232a6, content=呵呵,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Fri Jul 10 13:45:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32219, encodeId=5eba3221942, content=哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19691629579, createdName=zm0805, createdTime=Fri Jul 10 11:15:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32076, encodeId=dc7b320e623, content=微生物组火, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Thu Jul 09 19:58:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1249663, encodeId=ea89124966364, content=<a href='/topic/show?id=95264599452' target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Thu Jul 09 18:34:00 CST 2015, time=2015-07-09, status=1, ipAttribution=)]
    2015-07-12 huaxipanxing

    看看

    0

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    2015-07-11 neurowu
  4. [GetPortalCommentsPageByObjectIdResponse(id=1824604, encodeId=ef51182460413, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Mon Sep 14 10:34:00 CST 2015, time=2015-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32478, encodeId=eafc324e8dd, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=205, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun Jul 12 16:44:00 CST 2015, time=2015-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347052, encodeId=d1a5134e052a5, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Sat Jul 11 06:34:00 CST 2015, time=2015-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32232, encodeId=8a9732232a6, content=呵呵,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Fri Jul 10 13:45:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32219, encodeId=5eba3221942, content=哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19691629579, createdName=zm0805, createdTime=Fri Jul 10 11:15:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32076, encodeId=dc7b320e623, content=微生物组火, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Thu Jul 09 19:58:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1249663, encodeId=ea89124966364, content=<a href='/topic/show?id=95264599452' target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Thu Jul 09 18:34:00 CST 2015, time=2015-07-09, status=1, ipAttribution=)]
    2015-07-10 owlhealth

    呵呵,学习了

    0

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    2015-07-10 zm0805

    0

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    2015-07-09 medcardio

    微生物组火

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