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CELL:益生菌补充剂或对人体无效

2018-09-09 海北 MedSci原创

经验益生菌通常被健康个体消费,作为改善生活质量和预防疾病的手段。然而,关于益生菌肠粘膜定植功效的证据仍然稀少和有争议。

经验益生菌通常被健康个体消费,作为改善生活质量和预防疾病的手段。然而,关于益生菌肠粘膜定植功效的证据仍然稀少和有争议。
最近,来自魏茨曼科学研究所的研究人员在宏观上对小鼠和人类粘膜相关的肠道微生物组进行了表征,发现其只与粪便微生物组成部分相关。
在基线,和11种益生菌组合或安慰剂的消费期间,研究人员进行连续侵入性多组学测量,发现益生菌在通过肠道时仍然存活。
在定殖的但不是无菌的小鼠中,益生菌遇到显着的粘膜定植抗性。相比之下,人类的特征是人,区域和菌株特异性粘膜定植模式,由预测基线宿主和微生物组特征标记,但在粪便中存在的益生菌无法区分。
因此,益生菌诱导对粘膜群落结构和肠道转录组的短暂,个体化影响。
总的来说,经验性益生菌补充剂可能在普遍和持续影响肠粘膜方面受到限制,值得开发新的个性化益生菌方法。

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    2019-04-02 维他命
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  3. [GetPortalCommentsPageByObjectIdResponse(id=1961125, encodeId=85c9196112570, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Tue Apr 02 19:01:00 CST 2019, time=2019-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1870855, encodeId=7db718e085511, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Sun Jun 02 11:01:00 CST 2019, time=2019-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344144, encodeId=1c20344144e6, content=嗯嗯,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sun Sep 09 10:04:20 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344100, encodeId=b6543441002f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Sep 09 07:23:31 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 liumin1987

    嗯嗯,学习了。

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1961125, encodeId=85c9196112570, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Tue Apr 02 19:01:00 CST 2019, time=2019-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1870855, encodeId=7db718e085511, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Sun Jun 02 11:01:00 CST 2019, time=2019-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344144, encodeId=1c20344144e6, content=嗯嗯,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sun Sep 09 10:04:20 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344100, encodeId=b6543441002f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Sep 09 07:23:31 CST 2018, time=2018-09-09, status=1, ipAttribution=)]
    2018-09-09 明月清辉

    谢谢分享,学习了

    0

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