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JACC:癌症患者短期内动脉血栓栓塞风险显著增加

2017-08-15 nanchao.H MedSci原创

目前,癌症患者动脉血栓栓塞形成的风险尚未阐明。近日,在国际心血管权威杂志JACC上发表了一篇旨在分析评估这种关系的流行病学和对不同阶段癌症影响的临床研究。通过数据库,本研究纳入了2002年至2011年乳腺癌、肺癌、前列腺癌、结直肠肿瘤、膀胱癌、胰腺癌、胃癌或非霍奇金淋巴瘤的患者,并且根据人口统计学资料匹配了一个正常的参与者,每对研究对象从2012年开始进行分析观察。动脉血栓栓塞形成定义为心肌梗塞和

目前,癌症患者动脉血栓栓塞形成的风险尚未阐明。近日,在国际心血管权威杂志JACC上发表了一篇旨在分析评估这种关系的流行病学和对不同阶段癌症影响的临床研究。通过数据库,本研究纳入了2002年至2011年乳腺癌、肺癌、前列腺癌、结直肠肿瘤、膀胱癌、胰腺癌、胃癌或非霍奇金淋巴瘤的患者,并且根据人口统计学资料匹配了一个正常的参与者,每对研究对象从2012年开始进行分析观察。动脉血栓栓塞形成定义为心肌梗塞和缺血性卒中。最终,本研究共纳入279719对癌症和与其相应匹配的正常对照,癌症患者的6个月动脉血栓栓塞累积发病率为4.7%(95% [CI]: 4.6%-4.8%),对照的为2.2%(95% CI: 2.1%-2.2%)([HR]: 2.2; 95% CI: 2.1 -2.3)。其中,癌症患者心肌梗塞的6个月累积发病率为2.0%(95% CI: 1.9% -2.0%),对照的为0.7%(95% CI: 0.6%-0.7%),癌症患者缺血性卒中的6个月累积发病率为3.0%(95% CI: 2.9%-3.1%),对照的为1.6%(95% CI: 1.6% -1.7%)(HR: 1.9; 95% C

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    2018-02-22 hbwxf
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    2017-08-15 ishtar

    什么数据库?

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