Baidu
map

中国非小细胞肺癌免疫检查点抑制剂治疗专家共识(2020年版)

2021-04-20 国家癌症中心 中国肺癌杂志

非小细胞肺癌(non-small cell lung cancer, NSCLC)是肺癌最常见的病理类型。

中文标题:

中国非小细胞肺癌免疫检查点抑制剂治疗专家共识(2020年版)

发布机构:

国家癌症中心

发布日期:

2021-04-20

简要介绍:

非小细胞肺癌(non-small cell lung cancer, NSCLC)是肺癌最常见的病理类型。晚期NSCLC的系统性抗肿瘤治疗经历了化疗、靶向治疗及免疫治疗的变革,患者总体生存时间不断延长。免疫检查点抑制剂(immune checkpoint inhibitors, ICIs),尤其是程序性死亡分子-1(programmed cell death protein 1, PD-1)/程序性死亡分子配体-1(programmed death-ligand 1, PD-L1)抗体已成为表皮生长因子受体(epidermal growth factor receptor, EGFR)/间变性淋巴瘤激酶(anaplastic lymphoma kinase, ALK)阴性晚期NSCLC一线及二线的标准治疗和局部晚期NSCLC同步放化疗后标准治疗,并在辅助/新辅助治疗中显示出可喜的结果,改变了NSCLC整体治疗格局。随着越来越多的ICIs在国内获批肺癌适应证,中国临床肿瘤学会(Chinese Society of Clinical Oncology, CSCO)NSCLC专家委员会牵头,组织该领域的专家,结合2019年版专家共识,参考最新国内外文献、临床研究数据及系统评价,在专家共同讨论的基础上,达成统一意见并制定、更新本共识,为国内同行更好地应用ICIs治疗NSCLC提供参考意见。

相关资料下载:
[AttachmentFileName(sort=1, fileName=中国非小细胞肺癌免疫检查点抑制剂治疗专家共识(2020年版).pdf)] GetToolGuiderByIdResponse(projectId=1, id=d267b1c00229e338, title=中国非小细胞肺癌免疫检查点抑制剂治疗专家共识(2020年版), enTitle=, guiderFrom=中国肺癌杂志, authorId=0, author=, summary=非小细胞肺癌(non-small cell lung cancer, NSCLC)是肺癌最常见的病理类型。, cover=https://img.medsci.cn/20211221/1640096122071_5579292.jpg, journalId=0, articlesId=null, associationId=1931, associationName=国家癌症中心, associationIntro=国家癌症中心, copyright=0, guiderPublishedTime=Tue Apr 20 00:00:00 CST 2021, originalUrl=, linkOutUrl=, content=<p><span style="color: #333333;">非小细胞肺癌(non-small cell lung cancer, NSCLC)是肺癌最常见的病理类型。晚期NSCLC的系统性抗肿瘤治疗经历了化疗、靶向治疗及免疫治疗的变革,患者总体生存时间不断延长。免疫检查点抑制剂(immune checkpoint inhibitors, ICIs),尤其是程序性死亡分子-1(programmed cell death protein 1, PD-1)/程序性死亡分子配体-1(programmed death-ligand 1, PD-L1)抗体已成为表皮生长因子受体(epidermal growth factor receptor, EGFR)/间变性淋巴瘤激酶(anaplastic lymphoma kinase, ALK)阴性晚期NSCLC一线及二线的标准治疗和局部晚期NSCLC同步放化疗后标准治疗,并在辅助/新辅助治疗中显示出可喜的结果,改变了NSCLC整体治疗格局。随着越来越多的ICIs在国内获批肺癌适应证,中国临床肿瘤学会(Chinese Society of Clinical Oncology, CSCO)NSCLC专家委员会牵头,组织该领域的专家,结合2019年版专家共识,参考最新国内外文献、临床研究数据及系统评价,在专家共同讨论的基础上,达成统一意见并制定、更新本共识,为国内同行更好地应用ICIs治疗NSCLC提供参考意见。</span></p>, tagList=[TagDto(tagId=276, tagName=非小细胞肺癌), TagDto(tagId=428, tagName=肺癌), TagDto(tagId=36163, tagName=免疫检查点抑制剂)], categoryList=[CategoryDto(categoryId=5, categoryName=肿瘤, tenant=100), CategoryDto(categoryId=12, categoryName=呼吸, tenant=100), CategoryDto(categoryId=85, categoryName=指南&解读, tenant=100), CategoryDto(categoryId=21100, categoryName=达仁堂循证e学界, tenant=100)], articleKeywordId=0, articleKeyword=, articleKeywordNum=6, guiderKeywordId=36163, guiderKeyword=免疫检查点抑制剂, guiderKeywordNum=6, haveAttachments=1, attachmentList=null, guiderType=0, guiderArea=共识, guiderLanguage=0, guiderRegion=3, opened=0, paymentType=, paymentAmount=10, recommend=0, recommendEndTime=null, sticky=0, stickyEndTime=null, allHits=2816, appHits=352, showAppHits=0, pcHits=565, showPcHits=2458, likes=2, shares=62, comments=9, approvalStatus=1, publishedTime=Tue Dec 21 22:14:17 CST 2021, publishedTimeString=2021-04-20, pcVisible=1, appVisible=1, editorId=5579292, editor=FUNNYMAN, waterMark=0, formatted=0, memberCards=[], isPrivilege=0, deleted=0, version=2, createdBy=null, createdName=FUNNYMAN, createdTime=Tue Dec 21 22:22:27 CST 2021, updatedBy=5579292, updatedName=FUNNYMAN, updatedTime=Sat Jan 06 22:28:44 CST 2024, courseDetails=[], otherVersionGuiders=[], isGuiderMember=false, ipAttribution=, attachmentFileNameList=[AttachmentFileName(sort=1, fileName=中国非小细胞肺癌免疫检查点抑制剂治疗专家共识(2020年版).pdf)])
中国非小细胞肺癌免疫检查点抑制剂治疗专家共识(2020年版).pdf
下载请点击:
评论区 (8)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1249547, encodeId=3b38124954ebf, content=<a href='/topic/show?id=32af9938ec6' target=_blank style='color:#2F92EE;'>#非小细胞肺癌#</a><a href='/topic/show?id=0de5290588c' target=_blank style='color:#2F92EE;'>#免疫检查点抑制剂#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99387, encryptionId=32af9938ec6, topicName=非小细胞肺癌), TopicDto(id=29058, encryptionId=0de5290588c, topicName=免疫检查点抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Sep 17 06:48:27 CST 2022, time=2022-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224950, encodeId=7149122495019, content=好棒 学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PoZNgQYECm9EACoEhKXfFG8jvuG6NiaiaZiaSm2icb5c71MCHVXDOmE9huzaACteveKicMD7QIzh2Q3D5O5m9M1Rj4g/132, createdBy=6c992493334, createdName=天蓝00000, createdTime=Tue Jun 07 13:22:08 CST 2022, time=2022-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224497, encodeId=b8d8122449ee8, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=121e8191703, createdName=ms7000000135419910, createdTime=Sun Jun 05 06:26:22 CST 2022, time=2022-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208581, encodeId=fae512085814d, content=好资源,学习!, beContent=null, objectType=guider, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=00ec8098175, createdName=ms3000000771933475, createdTime=Mon Apr 04 18:41:20 CST 2022, time=2022-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1186981, encodeId=fb0f1186981bf, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/vJ58nhiaP6EY9qnGhDmrpQ8huOnnHCWI9aP6Y5MiaOVsvnmqsQpFNAPic914llgrAtvsBWdg3o189sDM1Z4HxShgQ/132, createdBy=74e82537825, createdName=1342515b7am, createdTime=Fri Jan 21 21:04:36 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1249547, encodeId=3b38124954ebf, content=<a href='/topic/show?id=32af9938ec6' target=_blank style='color:#2F92EE;'>#非小细胞肺癌#</a><a href='/topic/show?id=0de5290588c' target=_blank style='color:#2F92EE;'>#免疫检查点抑制剂#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99387, encryptionId=32af9938ec6, topicName=非小细胞肺癌), TopicDto(id=29058, encryptionId=0de5290588c, topicName=免疫检查点抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Sep 17 06:48:27 CST 2022, time=2022-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224950, encodeId=7149122495019, content=好棒 学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PoZNgQYECm9EACoEhKXfFG8jvuG6NiaiaZiaSm2icb5c71MCHVXDOmE9huzaACteveKicMD7QIzh2Q3D5O5m9M1Rj4g/132, createdBy=6c992493334, createdName=天蓝00000, createdTime=Tue Jun 07 13:22:08 CST 2022, time=2022-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224497, encodeId=b8d8122449ee8, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=121e8191703, createdName=ms7000000135419910, createdTime=Sun Jun 05 06:26:22 CST 2022, time=2022-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208581, encodeId=fae512085814d, content=好资源,学习!, beContent=null, objectType=guider, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=00ec8098175, createdName=ms3000000771933475, createdTime=Mon Apr 04 18:41:20 CST 2022, time=2022-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1186981, encodeId=fb0f1186981bf, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/vJ58nhiaP6EY9qnGhDmrpQ8huOnnHCWI9aP6Y5MiaOVsvnmqsQpFNAPic914llgrAtvsBWdg3o189sDM1Z4HxShgQ/132, createdBy=74e82537825, createdName=1342515b7am, createdTime=Fri Jan 21 21:04:36 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
    2022-06-07 天蓝00000

    好棒 学习了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1249547, encodeId=3b38124954ebf, content=<a href='/topic/show?id=32af9938ec6' target=_blank style='color:#2F92EE;'>#非小细胞肺癌#</a><a href='/topic/show?id=0de5290588c' target=_blank style='color:#2F92EE;'>#免疫检查点抑制剂#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99387, encryptionId=32af9938ec6, topicName=非小细胞肺癌), TopicDto(id=29058, encryptionId=0de5290588c, topicName=免疫检查点抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Sep 17 06:48:27 CST 2022, time=2022-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224950, encodeId=7149122495019, content=好棒 学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PoZNgQYECm9EACoEhKXfFG8jvuG6NiaiaZiaSm2icb5c71MCHVXDOmE9huzaACteveKicMD7QIzh2Q3D5O5m9M1Rj4g/132, createdBy=6c992493334, createdName=天蓝00000, createdTime=Tue Jun 07 13:22:08 CST 2022, time=2022-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224497, encodeId=b8d8122449ee8, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=121e8191703, createdName=ms7000000135419910, createdTime=Sun Jun 05 06:26:22 CST 2022, time=2022-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208581, encodeId=fae512085814d, content=好资源,学习!, beContent=null, objectType=guider, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=00ec8098175, createdName=ms3000000771933475, createdTime=Mon Apr 04 18:41:20 CST 2022, time=2022-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1186981, encodeId=fb0f1186981bf, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/vJ58nhiaP6EY9qnGhDmrpQ8huOnnHCWI9aP6Y5MiaOVsvnmqsQpFNAPic914llgrAtvsBWdg3o189sDM1Z4HxShgQ/132, createdBy=74e82537825, createdName=1342515b7am, createdTime=Fri Jan 21 21:04:36 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
    2022-06-05 ms7000000135419910

    学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1249547, encodeId=3b38124954ebf, content=<a href='/topic/show?id=32af9938ec6' target=_blank style='color:#2F92EE;'>#非小细胞肺癌#</a><a href='/topic/show?id=0de5290588c' target=_blank style='color:#2F92EE;'>#免疫检查点抑制剂#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99387, encryptionId=32af9938ec6, topicName=非小细胞肺癌), TopicDto(id=29058, encryptionId=0de5290588c, topicName=免疫检查点抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Sep 17 06:48:27 CST 2022, time=2022-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224950, encodeId=7149122495019, content=好棒 学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PoZNgQYECm9EACoEhKXfFG8jvuG6NiaiaZiaSm2icb5c71MCHVXDOmE9huzaACteveKicMD7QIzh2Q3D5O5m9M1Rj4g/132, createdBy=6c992493334, createdName=天蓝00000, createdTime=Tue Jun 07 13:22:08 CST 2022, time=2022-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224497, encodeId=b8d8122449ee8, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=121e8191703, createdName=ms7000000135419910, createdTime=Sun Jun 05 06:26:22 CST 2022, time=2022-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208581, encodeId=fae512085814d, content=好资源,学习!, beContent=null, objectType=guider, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=00ec8098175, createdName=ms3000000771933475, createdTime=Mon Apr 04 18:41:20 CST 2022, time=2022-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1186981, encodeId=fb0f1186981bf, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/vJ58nhiaP6EY9qnGhDmrpQ8huOnnHCWI9aP6Y5MiaOVsvnmqsQpFNAPic914llgrAtvsBWdg3o189sDM1Z4HxShgQ/132, createdBy=74e82537825, createdName=1342515b7am, createdTime=Fri Jan 21 21:04:36 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
    2022-04-04 ms3000000771933475

    好资源,学习!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1249547, encodeId=3b38124954ebf, content=<a href='/topic/show?id=32af9938ec6' target=_blank style='color:#2F92EE;'>#非小细胞肺癌#</a><a href='/topic/show?id=0de5290588c' target=_blank style='color:#2F92EE;'>#免疫检查点抑制剂#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99387, encryptionId=32af9938ec6, topicName=非小细胞肺癌), TopicDto(id=29058, encryptionId=0de5290588c, topicName=免疫检查点抑制剂)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Sep 17 06:48:27 CST 2022, time=2022-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224950, encodeId=7149122495019, content=好棒 学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PoZNgQYECm9EACoEhKXfFG8jvuG6NiaiaZiaSm2icb5c71MCHVXDOmE9huzaACteveKicMD7QIzh2Q3D5O5m9M1Rj4g/132, createdBy=6c992493334, createdName=天蓝00000, createdTime=Tue Jun 07 13:22:08 CST 2022, time=2022-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1224497, encodeId=b8d8122449ee8, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=121e8191703, createdName=ms7000000135419910, createdTime=Sun Jun 05 06:26:22 CST 2022, time=2022-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208581, encodeId=fae512085814d, content=好资源,学习!, beContent=null, objectType=guider, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=00ec8098175, createdName=ms3000000771933475, createdTime=Mon Apr 04 18:41:20 CST 2022, time=2022-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1186981, encodeId=fb0f1186981bf, content=学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/vJ58nhiaP6EY9qnGhDmrpQ8huOnnHCWI9aP6Y5MiaOVsvnmqsQpFNAPic914llgrAtvsBWdg3o189sDM1Z4HxShgQ/132, createdBy=74e82537825, createdName=1342515b7am, createdTime=Fri Jan 21 21:04:36 CST 2022, time=2022-01-21, status=1, ipAttribution=)]
    2022-01-21 1342515b7am

    学习了

    0

拓展阅读

免疫检查点抑制剂相关血液毒性处理的临床诊疗建议

中国肿瘤科相关专家小组(统称) · 2019-10-30

免疫检查点抑制剂相关肾脏不良反应的临床诊治建议

国外肿瘤科相关专家小组(统称) · 2019-10-30

免疫检查点抑制剂相关皮肤不良反应诊治建议

中国肿瘤科相关专家小组(统称) · 2019-10-25

免疫检查点抑制剂相关神经系统不良反应的临床诊治建议

中国肿瘤科相关专家小组(统称) · 2019-10-30

免疫检查点抑制剂相关消化系统不良反应的临床诊治建议

中国肿瘤科相关专家小组(统称) · 2019-10-30

Baidu
map
Baidu
map
Baidu
map