Journal of Pharmacokinetics and Biopharmaceutics is devoted to illustrating the importance of pharmacokinetic and biopharmaceutical applications in the understanding of drug action design therapy and evaluation. Experimental and theoretical articles deal with topics such as the kinetics of drug disposition; clinical pharmacokinetics; the time course of pharmacological response; and factors affecting formation and disposition of metabolites. Discontinued - replaced by Journal of Pharmacokinetics and Pharmacodynamics.