The field of haemostasis and thrombosis has witnessed significant developments during the last few decades. The upcoming of biochemistry, cell biology and later of molecular biology as new research tools has constantly been reflected in the former "Haemostasis". Nevertheless, the journal continued to devote many of its pages to traditional clinical pathophysiology. The new name "Pathophysiology of Haemostasis and Thrombosis" emphasizes the importance of this constant approach in a world of changing fashions. The journal features original contributions reporting the latest findings on the pathology, physiology and biochemistry of hemorrhagic disease and thrombosis. In addition to in-depth studies of such topics as blood coagulation factors, fibrinolysis, platelets and vascular biology, readers will find extensive data on clinical results with heparin, oral anticoagulants and newer anti-thrombotics. Practical information on the diagnosis and treatment of bleeding disorders and on fibrinolytic treatment are also provided. These experimental and clinical investigations are supported by occasional authoritative reviews to make the journal a full record of current research on thrombosis and haemostasis and its clinical implications.