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Pharmacogenetics is devoted to the rapid publication of research papers, brief review articles and short communications on genetic variation in response to drugs and other chemicals in humans and animals. Pharmacogenetics seeks to identify and characterize polymorphic genes, encoding drug metabolizing enzymes, drug receptors and drug transporters in man and animals. It studies the effects of their expression on the disposition and metabolism of foreign chemicals, together with the cellular and clinical responses they evoke. Emphasis is given to an understanding of the genetic mechanisms of species differences in foreign compound metabolism and responsiveness, and to the regulation of drug metabolizing enzymes and their genes. Discontinued - now Pharmacogenetics and Genomics (1744-6872).
