Molecular Pharmacology welcomes manuscripts for consideration that report new information on drug action or selective toxicity at the molecular level. The Editors encourage submissions that shed light upon molecular mechanisms. These may include, for example, studies of receptors, signaling, pathways, enzymes,channels, and transcriptional mechanisms. Studies that report the development of novel reagents or technologies that are of broad applicability or yield new molecular insights are also encouraged. While Molecular Pharmacology attempts to publish studies with a strong component of biological experimentation, the journal also welcomes studies that involve molecular modeling relevant to drug design or drug action.