期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (2)
Limb-girdle muscular dystrophy R12 (LGMD-R12) is caused by recessive mutations in the Anoctamin-5 gene (ANO5, TMEM16E). Although ANO5 myopathy is not ......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (3)
Suppressing mineralocorticoid receptor (MR) activity with MR antagonists is therapeutic for chronic skeletal muscle pathology in Duchenne muscular dys......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (4)
Redox homeostasis is elemental for the normal physiology of all cell types. Cells use multiple mechanisms to tightly regulate the redox balance. The o......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (4)
The breakthrough technology for reprogramming somatic cells into induced pluripotent stem cells (iPSCs) has created a new path for science and medicin......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (5)
Although great effort has been expended to understand cancer's origins, less attention has been given to the primary cause of cancer deaths-cancer rec......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (5)
Mechanical forces are critical physical cues that can affect numerous cellular processes regulating the development, tissue maintenance, and functiona......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)
The size of the satellite cell pool is reduced in estradiol (E-2)-deficient female mice and humans. Here, we use a combination of in vivo and in vitro......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (1)
Inward-rectifier potassium channel 7.1 (Kir7.1) is present in the polarized epithelium, including the retinal pigmented epithelium. A single amino aci......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (4)
tNovel insights on regulation of gene expression mechanisms highlight the pivotal role of epitranscriptomic modifications on decision about transcript......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (4)
Conditions that cause the loss of epithelial barrier integrity are often accompanied by dysregulation of tight junction protein expression and/or loca......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (5)
Hypertension is characterized by increased sodium (Na+) reabsorption along the aldosterone-sensitive distal nephron (ASDN) as well as chronic systemic......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (6)
Mutations in tripartite motif-containing protein 32 (TRIM32), especially in NHL repeats, have been found in skeletal muscle in patients with type 2H l......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)
Hyaluronan is a versatile macromolecule capable of an exceptional range of functions from cushioning and hydration to dynamic signaling in development......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)
Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass loss, also known as muscle atrophy. The balance between musc......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)
Obesity is a widespread public health problem with profound medical consequences and its burden is increasing worldwide. Obesity causes significant mo......