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Sex differences in the involvement of skeletal and cardiac muscles in myopathic Ano5-/- mice

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (2)

Limb-girdle muscular dystrophy R12 (LGMD-R12) is caused by recessive mutations in the Anoctamin-5 gene (ANO5, TMEM16E). Although ANO5 myopathy is not ......

JIF:3.452

Myeloid mineralocorticoid receptors contribute to skeletal muscle repair in muscular dystrophy and acute muscle injury

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (3)

Suppressing mineralocorticoid receptor (MR) activity with MR antagonists is therapeutic for chronic skeletal muscle pathology in Duchenne muscular dys......

JIF:3.452

Regulation of immune cell function by nicotinamide nucleotide transhydrogenase

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (4)

Redox homeostasis is elemental for the normal physiology of all cell types. Cells use multiple mechanisms to tightly regulate the redox balance. The o......

JIF:3.452

Long noncoding RNAs in induced pluripotent stem cells and their differentiation

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (4)

The breakthrough technology for reprogramming somatic cells into induced pluripotent stem cells (iPSCs) has created a new path for science and medicin......

JIF:3.452

Enzyme trafficking and coclustering precede and accurately predict human breast cancer recurrences: an interdisciplinary review

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (5)

Although great effort has been expended to understand cancer's origins, less attention has been given to the primary cause of cancer deaths-cancer rec......

JIF:3.452

Role of mechanosensitive channels/receptors in atherosclerosis

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (5)

Mechanical forces are critical physical cues that can affect numerous cellular processes regulating the development, tissue maintenance, and functiona......

JIF:3.452

Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)

The size of the satellite cell pool is reduced in estradiol (E-2)-deficient female mice and humans. Here, we use a combination of in vivo and in vitro......

JIF:3.452

Kir7.1 disease mutant T153I within the inner pore affects K+ conduction

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (1)

Inward-rectifier potassium channel 7.1 (Kir7.1) is present in the polarized epithelium, including the retinal pigmented epithelium. A single amino aci......

JIF:3.452

Deciphering impact of single nucleotide polymorphisms on cotranscriptional modification in CCM gene mRNAs

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (4)

tNovel insights on regulation of gene expression mechanisms highlight the pivotal role of epitranscriptomic modifications on decision about transcript......

JIF:3.452

Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (4)

Conditions that cause the loss of epithelial barrier integrity are often accompanied by dysregulation of tight junction protein expression and/or loca......

JIF:3.452

Interleukin 6 mediated activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (5)

Hypertension is characterized by increased sodium (Na+) reabsorption along the aldosterone-sensitive distal nephron (ASDN) as well as chronic systemic......

JIF:3.452

Tripartite motif-containing protein 32 regulates Ca2 1 movement in skeletal muscle

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 323 (6)

Mutations in tripartite motif-containing protein 32 (TRIM32), especially in NHL repeats, have been found in skeletal muscle in patients with type 2H l......

JIF:3.452

Mechanisms of coordinating hyaluronan and glycosaminoglycan production by nucleotide sugars

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)

Hyaluronan is a versatile macromolecule capable of an exceptional range of functions from cushioning and hydration to dynamic signaling in development......

JIF:3.452

Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)

Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass loss, also known as muscle atrophy. The balance between musc......

JIF:3.452

Thermogenic T cells: a cell therapy for obesity?

期刊: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022; 322 (6)

Obesity is a widespread public health problem with profound medical consequences and its burden is increasing worldwide. Obesity causes significant mo......

JIF:3.452

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