期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (9-10)
Indazole-based HDAC6 inhibitors with novel zinc-binding modifications were synthesized and evaluated to determine their potential to inhibit HDAC6. Th......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; ()
Gastric cancer (GC) is one of the most prevalent malignancies in the world, with a high mortality rate in both women and men. Conventional treatments,......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (3)
Engineering approaches using antibody drug conjugates (ADCs) and bispecific antibodies (bsAbs) are designed to overcome the limitations of conventiona......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (7)
Macrophages within the tumor microenvironment (TME), referred to as tumor-associated macrophages (TAMs), are involved in various aspects of tumor prog......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; ()
The reprogramming of lipid metabolism and its association with oncogenic signaling pathways within the tumor microenvironment (TME) have emerged as si......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; ()
Chaenomeles plants belong to the Rosaceae family and include five species, Chaenomeles speciosa (Sweet) Nakai, Chaenomeles sinensis (Thouin) Koehne, C......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (9-10)
The fact that mitochondria play a crucial part in energy generation has led to the nickname powerhouses of the cell being applied to them. They also p......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (3)
Induction of the brown adipocyte-like phenotype in white adipocytes (fat browning) is considered a promising therapeutic strategy to treat obesity. Na......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (7)
Paeoniflorin is the major active compound of total glycoside of paeony in Paeonia lactiflora Pall. Although several aspects of beneficial effects of p......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (4)
Epidermal growth factor (EGF) has been used in wound management and regenerative medicine since the late 1980s. It has been widely utilized for a long......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (9-10)
In a previous study, we discovered that the ethanolic extract of sea buckthorn (Hippophae rhamnoides) fruits exhibited anti-osteoporosis effects both ......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (7)
As the ubiquitin-proteasome system (UPS) regulates almost every biological process, the dysregulation or aberrant expression of the UPS components cau......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (8)
Pyrrolizidine alkaloids (PAs) are potent hepatotoxins that can cause liver damage. Hyperoside (Hyp), a natural flavonoid, can be extracted from medici......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (5)
Gliclazide metabolism is mediated by genetically polymorphic CYP2C9 and CYP2C19 enzymes. We investigated the effects of CYP2C9 and CYP2C19 genetic pol......
期刊: ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (8)
Green synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 &......