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Biotransformation of rare earth oxide nanoparticles eliciting microbiota imbalance

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Disruption of microbiota balance may result in severe diseases in animals and phytotoxicity in plants. While substantial concerns have been......

Effects of water-soluble components of atmospheric particulates from rare earth mining areas in China on lung cancer cell cycle

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background This study aims to investigate the effects of water soluble particulate matter (WSPM) on the viability and protein expression profile of hu......

Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Micro- and nanoplastic pollution has become a global environmental problem. Nanoplastics in the environment are still hard to detect becaus......

Cytotoxicity analysis of biomass combustion particles in human pulmonary alveolar epithelial cells on an air-liquid interface/dynamic culture platform

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Exposure to indoor air pollution from solid fuel combustion is associated with lung diseases and cancer. This study investigated the cytoto......

Airborne particulate matters induce thrombopoiesis from megakaryocytes through regulating mitochondrial oxidative phosphorylation

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Although airborne fine particulate matter (PM) pollution has been demonstrated as an independent risk factor for pulmonary and cardiovascul......

Titanium dioxide nanoparticles enhance thrombosis through triggering the phosphatidylserine exposure and procoagulant activation of red blood cells

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Expanding biomedical application of anatase titanium dioxide (TiO2) nanoparticles (NPs) is raising the public concern on its potential heal......

The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Objective Up to 44% of particulates of food-grade titanium dioxide (TiO2) are in nanoscale, while the effect and combined effect of which with other s......

Airborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Particulate matter (PM) is strongly linked to human health and has detrimental effects on the eye. Studies have, however, focused on the oc......

Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Air pollution exposure and idiopathic pulmonary fibrosis (IPF) cause a poor prognosis after SARS-CoV-2 infection, but the underlying mechan......

Chronic exposure to diesel exhaust may cause small airway wall thickening without lumen narrowing: a quantitative computerized tomography study in Chinese diesel engine testers

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Diesel exhaust (DE) is a major source of ultrafine particulate matters (PM) in ambient air and contaminates many occupational settings. Air......

Cobalt oxide nanoparticles induce oxidative stress and alter electromechanical function in rat ventricular myocytes

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1)

Background Nanotoxicology is an increasingly relevant field and sound paradigms on how inhaled nanoparticles (NPs) interact with organs at the cellula......

Activation of synovial fibroblasts from patients at revision of their metal-on-metal total hip arthroplasty

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2020; 17 (1)

Background The toxicity of released metallic particles generated in metal-on-metal (MoM) total hip arthroplasty (THA) using cobalt chromium (CoCr) has......

Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2020; 17 (1)

Background With the development of zinc oxide nanoparticles (ZnO NPs) in the field of nanotechnology, their toxicological effects are attracting incre......

Occupational exposure to carbon black nanoparticles increases inflammatory vascular disease risk: an implication of an ex vivo biosensor assay

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2020; 17 (1)

Background Among manufactured or engineered nanoparticles, carbon black (CB) has largest production worldwide and is also an occupational respiratory ......

Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE(-/-) mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage

期刊: PARTICLE AND FIBRE TOXICOLOGY, 2020; 17 (1)

Background: The biosafety concern of silica nanoparticles (SiNPs) is rapidly expanding alongside with its mass production and extensive applications. ......

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