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Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19

Li, HH; Liu, CC; Hsu, TW; Lin, JH; Hsu, JW; Li, AFY; Yeh, YC; Hung, SC; Hsu, HS

Hsu, HS (corresponding author), Natl Yang Ming Chiao Tung Univ, Sch Med, Inst Emergency & Crit Care Med, 155,Sec 2,Linong St, Taipei 112, Taiwan.; Hsu, HS (corresponding author), Taipei Vet Gen Hosp, Dept Surg, Div Thorac Surg, Taipei, Taiwan.; Hung, SC (corresponding author), China Med Univ, Inst New Drug Dev, Biomed Sci, 7F,6 Xueshi Rd, Taichung 404, Taiwan.; Hung, SC (corresponding author), China Med Univ Hosp, Integrat Stem Cell Ctr, Dept Orthoped, Taichung, Taiwan.; Hung, SC (corresponding

PARTICLE AND FIBRE TOXICOLOGY, 2021; 18 (1):

Abstract

Background Air pollution exposure and idiopathic pulmonary fibrosis (IPF) cause a poor prognosis after SARS-CoV-2 infection, but the underlying mechan......

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