期刊: DRUG RESISTANCE UPDATES, 2021; 54 ()
Tumor chemosensitivity testing plays a pivotal role in the optimal selection of chemotherapeutic regimens for cancer patients in a personalized manner......
期刊: DRUG RESISTANCE UPDATES, 2021; 57 ()
The cytotoxic anti-cancer drugs cisplatin, paclitaxel, doxorubicin, 5-fluorouracil (5-FU), as well as targeted drugs including imatinib, erlotinib, an......
期刊: DRUG RESISTANCE UPDATES, 2021; 54 ()
ATP-binding cassette (ABC) transporters mediate the ATP-driven translocation of structurally and mechanistically distinct substrates against steep con......
期刊: DRUG RESISTANCE UPDATES, 2021; 56 ()
Immunotherapies such as CAR-T cell transfer and antibody-targeted therapy have produced promising clinical outcomes in patients with advanced and meta......
期刊: DRUG RESISTANCE UPDATES, 2020; 48 ()
Drug resistance is a major obstacle in the field of pre-clinical and clinical therapeutics. The development of novel technologies and targeted therapi......
期刊: DRUG RESISTANCE UPDATES, 2020; 49 ()
Chemotherapy continues to be a major treatment strategy for various human malignancies. However, the frequent emergence of chemoresistance compromises......
期刊: DRUG RESISTANCE UPDATES, 2020; 49 ()
The presence of multidrug resistance (MDR) in malignant tumors is one of the primary causes of treatment failure in cancer chemotherapy. The overexpre......
期刊: DRUG RESISTANCE UPDATES, 2020; 50 ()
Chemoresistance including intrinsic and acquired anticancer drug resistance continues to be a primary hindrance towards curative cancer treatment. The......
期刊: DRUG RESISTANCE UPDATES, 2020; 53 ()
Despite the development of targeted therapy, drug resistance remains a primary hindrance to curative treatment of various cancers. Among several novel......
期刊: DRUG RESISTANCE UPDATES, 2020; 49 ()
Cancer continues to be a leading threat to human health and life. Resistance to anti-cancer drugs is a major impediment towards efficacious cancer tre......
期刊: DRUG RESISTANCE UPDATES, 2018; 41 ()
The successful treatment of cancer has significantly improved as a result of targeted therapy and immunotherapy. However, during chemotherapy, cancer ......
期刊: DRUG RESISTANCE UPDATES, 2022; 61 ()
Despite the rapid advancement in the introduction of new drugs for cancer therapy, the frequent emergence of drug resistance leads to disease progress......
期刊: DRUG RESISTANCE UPDATES, 2022; 65 ()
Background: Colorectal cancer (CRC) is the 3rd most common cancer worldwide. CircRNAs are promising novel biomarkers for CRC. T regulatory (Treg) cell......
期刊: DRUG RESISTANCE UPDATES, 2022; 65 ()
Aims: This study aimed to identify mechanisms of drug resistance to the combination of vemurafenib, irinotecan, and cetuximab (VIC) in BRAFV600E metas......
期刊: DRUG RESISTANCE UPDATES, 2022; 65 ()
Infections caused by multidrug-resistant fungi pose a devastating threat to human health worldwide, making new antifungal strategies urgently desired.......