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Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update

Dong, JY; Qin, ZD; Zhang, WD; Cheng, G; Yehuda, AG; Ashby, CR; Chen, ZS; Cheng, XD; Qin, JJ

Qin, JJ (corresponding author), Zhejiang Chinese Med Univ, Coll Pharmaceut Sci, 548 Binwen Rd, Hangzhou 310053, Zhejiang, Peoples R China.; Chen, ZS (corresponding author), St Johns Univ, Coll Pharm & Hlth Sci, 8000 Utopia Pkwy, New York, NY 11439 USA.; Cheng, XD (corresponding author), Zhejiang Canc Hosp, Dept Abdominal Canc Surg, Banshan Rd 1, Hangzhou 310022, Zhejiang, Peoples R China.

DRUG RESISTANCE UPDATES, 2020; 49 ():

Abstract

The presence of multidrug resistance (MDR) in malignant tumors is one of the primary causes of treatment failure in cancer chemotherapy. The overexpre......

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