期刊: APOPTOSIS IN HEALTH AND DISEASE, PT A, 2021; 125 ()
Mitochondria, conserved intracellular organelles best known as the powerhouse of cells for generating ATP, play an important role in apoptosis. Oxidat......
Protein kinases use ATP to phosphorylate other proteins. Phosphorylation (p) universally orchestrates a fine-tuned network modulating a multitude of b......
期刊: INFLAMMATORY DISORDERS, PT A, 2020; 119 ()
Interleukin (IL)-34 is a recently discovered cytokine and ligand of the colony-stimulating factor (CSF)-1 receptor. Although CSF-1 and IL-34 share sim......
期刊: INFLAMMATORY DISORDERS - PT B, 2020; 120 ()
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival inflammation and bone loss. Periodontitis is associated ......
期刊: ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY, VOL 121, 2020; 121 ()
Forkhead Box P3 (FOXP3) is a key transcriptional regulator of regulatory T cells (Tregs), especially for its function of immune suppression. The speci......
期刊: ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY, VOL 121, 2020; 121 ()
DNA methyltransferases (DNMTs) not only play key roles in epigenetic gene regulation, but also serve as emerging targets for several diseases, especia......
Non-heme iron enzymes catalyze a wide range of chemical transformations, serving as one of the key types of tailoring enzymes in the biosynthesis of n......
期刊: THERAPEUTIC PROTEINS AND PEPTIDES, 2018; 112 ()
Many therapeutic macromolecules must enter cells to take their action. However, their treatment outcomes are often hampered by their poor transportati......
期刊: CHROMATIN REMODELLING AND IMMUNITY, 2017; 106 ( )
Chromatin remodeling, an important facet of the regulation of gene expression in eukaryotes, is performed by two major types of multisubunit complexes......
期刊: CHROMATIN PROTEINS AND TRANSCRIPTION FACTORS AS THERAPEUTIC TARGETS, 2017; 107 ( )
The balance of CD4(+)CD25(+)FOXP3(+) regulatory T cells (Tregs) and effector T cells plays a key role in maintaining immune homeostasis, while the imb......