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Effects of the IQ1 motif of Drosophila myosin-5 on the calcium interaction of calmodulin

期刊: CELL CALCIUM, 2022; 103 ()

In Drosophila compound eyes, myosin-5 (DmMyo5) plays a key role in organelle transportation, including transporting pigment granules from the distal e......

JIF:5.802

Mechanosensitive Piezo1 channel in rat epididymal epithelial cells promotes transepithelial K+ secretion

期刊: CELL CALCIUM, 2022; 104 ()

The Piezo1 channel, a mechanosensitive channel that exhibit a preference for Ca2+, play multifarious physiological and pathological roles in the endot......

JIF:5.802

The calcium signaling enzyme CD38-a paradigm for membrane topology defining distinct protein functions

期刊: CELL CALCIUM, 2022; 101 ()

CD38 is a single-pass transmembrane enzyme catalyzing the synthesis of two nucleotide second messengers, cyclic ADP-ribose (cADPR) from NAD and nicoti......

JIF:5.802

Mutations and clinical significance of calcium voltage-gated channel subunit alpha 1E (CACNA1E) in non-small cell lung cancer

期刊: CELL CALCIUM, 2022; 102 ()

CACNA1E is a gene encoding the ion-conducting alpha 1 subunit of R-type voltage-dependent calcium channels, whose roles in tumorigenesis remain to be ......

JIF:5.802

Lysosomal potassium channels

期刊: CELL CALCIUM, 2022; 102 ()

The lysosome is an important membrane-bound acidic organelle that is regarded as the degradative center as well as multifunctional signaling hub. It d......

JIF:5.802

TRPC4 ion channel regulations by small-molecular inhibitors and calmodulin

期刊: CELL CALCIUM, 2021; 95 ()

TRPC4 ion channel was reported to be regulated by small molecular inhibitors and calmodulin. We discuss these findings in the context of other members......

Mechanosensitive Piezo1 in endothelial cells promotes angiogenesis to support bone fracture repair

期刊: CELL CALCIUM, 2021; 97 ()

Piezo1, a calcium-permeable non-selective cationic channel that senses mechanical stimulation in multicellular organisms, mediates various biological ......

The expression of constitutively active CPK3 impairs potassium uptake and transport in Arabidopsis under low K plus stress

期刊: CELL CALCIUM, 2021; 98 ()

Potassium (K+) is a vital cation and is involved in multiple physiological functions in plants. K+ uptake from outer medium by roots is a tightly regu......

Attenuation of the extracellular matrix increases the number of synapses but suppresses synaptic plasticity through upregulation of SK channels

期刊: CELL CALCIUM, 2021; 96 ()

The effect of brain extracellular matrix (ECM) on synaptic plasticity remains controversial. Here, we show that targeted enzymatic attenuation with ch......

Lysosomal ion channels involved in cellular entry and uncoating of enveloped viruses: Implications for therapeutic strategies against SARS-CoV-2

期刊: CELL CALCIUM, 2021; 94 ()

Ion channels are necessary for correct lysosomal function including degradation of cargoes originating from endocytosis. Almost all enveloped viruses,......

Cimifugin relieves pruritus in psoriasis by inhibiting TRPV4

期刊: CELL CALCIUM, 2021; 97 ()

Psoriasis is an immune-mediated chronic inflammatory skin disease characterized by erythema, scales, and infiltration of the skin, which causes delete......

Involvement of TRPV1 and TRPA1 in the modulation of pacemaker potentials in the mouse ileum

期刊: CELL CALCIUM, 2021; 97 ()

Background: The roles of transient receptor potential cation channel, subfamily V, member 1 (TRPV1) and subfamily A, member 1 (TRPA1) in mechanisms of......

Piezo1 impairs hepatocellular tumor growth via deregulation of the MAPK-mediated YAP signaling pathway

期刊: CELL CALCIUM, 2021; 95 ()

* Corresponding author at: Lingnan Medical Research Center, Guangzhou University of Chinese Medicine and the First Affiliated Hospital of Guangzhou Un......

Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans

期刊: CELL CALCIUM, 2021; 93 ()

Inositol polyphosphate multikinase (IPMK) is a conserved protein that initiates the production of inositol phosphate intracellular messengers and is c......

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