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The calcium signaling enzyme CD38-a paradigm for membrane topology defining distinct protein functions

Lee, HC; Deng, QW; Zhao, YJ

Lee, HC; Zhao, YJ (通讯作者),Peking Univ, State Key Lab Chem Oncogen, Key Lab Chem Genom, Shenzhen Grad Sch, Shenzhen 518055, Peoples R China.;Zhao, YJ (通讯作者),Chinese Univ Hong Kong, Sch Life & Hlth Sci, Ciechanover Inst Precis & Regenerat Med, Shenzhen 518172, Peoples R China.

CELL CALCIUM, 2022; 101 ():

Abstract

CD38 is a single-pass transmembrane enzyme catalyzing the synthesis of two nucleotide second messengers, cyclic ADP-ribose (cADPR) from NAD and nicoti......

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